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Literature summary for 1.13.12.5 extracted from

  • Wang, J.; Guo, W.; Long, C.; Zhou, H.; Wang, H.; Sun, X.
    The split Renilla luciferase complementation assay is useful for identifying the interaction of Epstein-Barr virus protein kinase BGLF4 and aheat shock protein Hsp90 (2016), Acta Virol., 60, 62-70 .
    View publication on PubMed

Application

Application Comment Organism
diagnostics the split Renilla luciferase complementation assay (SRLCA) is one of the techniques that detect protein-protein interactions. The SRLCA is based on the complementation of the LN and LC non-functional halves of Renilla luciferase fused to possibly interacting proteins which after interaction form a functional enzyme and emit luminescence. The SRLCA can specifically detect the BGLF4/Hsp90 interaction and provide a reference to develop inhibitors that disrupt the Epstein-Barr virus kinase BGLF4 and heat shock protein Hsp90 interaction Renilla reniformis

Organism

Organism UniProt Comment Textmining
Renilla reniformis P27652
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Synonyms

Synonyms Comment Organism
Renilla luciferase
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Renilla reniformis