Any feedback?
Literature summary for 1.13.99.1 extracted from
- Increased expression of myo-inositol oxygenase is involved in the tubulointerstitial injury of diabetic nephropathy (2009), Exp. Clin. Endocrinol. Diabetes, 117, 257-265.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | increased secretion in a dose-dependent manner after high-glucose treatment | Rattus norvegicus |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| transfection into NRK-52E cells | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
control group and diabetes group | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| renal cortex | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| myo-inositol + O2 | - |
Rattus norvegicus | D-glucuronic acid + H2O | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MIOX | - |
Rattus norvegicus |
| Myo-inositol oxygenase | - |
Rattus norvegicus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rattus norvegicus | diabetic, nephropathy | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | increased expression in diabetic kidneys may contribute to tubulointerstitial injury and development of diabetic nephropathy | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
