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Literature summary for 1.14.11.28 extracted from

  • Shibasaki, T.; Sakurai, W.; Hasegawa, A.; Uosaki, Y.; Mori, H.; Yoshida, M.; Ozaki, A.
    Substrate selectivities of proline hydroxylases (1999), Tetrahedron Lett., 40, 5227-5230.
No PubMed abstract available
Search for more literature for 1.14.11.28

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Streptomyces sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.2
-
 L-proline
-
 Streptomyces sp.
0.4
-
 L-proline
-
 Streptomyces sp.
2.1
-
 L-2-azetidinecarboxylic acid
-
 Streptomyces sp.
3.8
-
 L-pipecolic acid
-
 Streptomyces sp.
8.4
-
 3,4-dehydro-L-proline
-
 Streptomyces sp.
100
-
 L-pipecolic acid
-
 Streptomyces sp.

Organism

Organism UniProt Comment Textmining
Streptomyces sp.
-
 strainTH1
-
Streptomyces sp. TH1
-
 strainTH1
-

Purification (Commentary)

Purification (Comment) Organism
2 chromatographic steps to homogeneity Streptomyces sp.

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
 Streptomyces sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-dehydro-L-proline + 2-oxoglutarate + O2
-
 Streptomyces sp. cis-3,4-epoxy-L-proline + succinate + CO2
-
 ?
3,4-dehydro-L-proline + 2-oxoglutarate + O2
-
 Streptomyces sp. TH1 cis-3,4-epoxy-L-proline + succinate + CO2
-
 ?
L-2-azetidinecarboxylic acid + 2-oxoglutarate + O2
-
 Streptomyces sp. cis-3-hydroxyazetidine-L-2-carboxylic acid + succinate + CO2
-
 ?
L-2-azetidinecarboxylic acid + 2-oxoglutarate + O2
-
 Streptomyces sp. TH1 cis-3-hydroxyazetidine-L-2-carboxylic acid + succinate + CO2
-
 ?
L-pipecolic acid + 2-oxoglutarate + O2
-
 Streptomyces sp. cis-3-hydroxy-L-pipecolic acid + succinate + CO2
-
 ?
L-pipecolic acid + 2-oxoglutarate + O2
-
 Streptomyces sp. TH1 cis-3-hydroxy-L-pipecolic acid + succinate + CO2
-
 ?
L-proline + 2-oxoglutarate + O2
-
 Streptomyces sp. cis-3-hydroxy-L-proline + succinate + CO2
-
 ?
L-proline + 2-oxoglutarate + O2
-
 Streptomyces sp. TH1 cis-3-hydroxy-L-proline + succinate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
proline 3-hydroxylase type I
-
 Streptomyces sp.
proline 3-hydroxylase type II
-
 Streptomyces sp.