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Literature summary for 1.14.11.33 extracted from

  • Duncan, T.; Trewick, S.C.; Koivisto, P.; Bates, P.A.; Lindahl, T.; Sedgwick, B.
    Reversal of DNA alkylation damage by two human dioxygenases (2002), Proc. Natl. Acad. Sci. USA, 99, 16660-5.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm diffuse presence of YFP-ABH3 construct Homo sapiens 5737
-
nucleolus accumulation of YFP-ABH2 construct Homo sapiens 5730
-
nucleoplasm diffuse presence of YFP-ABH2 construct Homo sapiens 5654
-
nucleus diffuse presence of YFP-ABH3 construct Homo sapiens 5634
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bladder high ABH2 and ABH3 mRNA levels Homo sapiens
-
colon high ABH3 mRNA levels Homo sapiens
-
HeLa cell high ABH2 mRNA levels Homo sapiens
-
liver high ABH2 mRNA levels Homo sapiens
-
prostate gland high ABH3 mRNA levels Homo sapiens
-
spleen high ABH3 mRNA levels Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-ethyladenine + O2 + 2-oxoglutarate
-
Homo sapiens adenine + CO2 + acetaldehyde + succinate + H+
-
?
1-methyladenine + O2 + 2-oxoglutarate
-
Homo sapiens adenine + CO2 + formaldehyde + succinate + H+
-
?
3-methylcytosine + O2 + 2-oxoglutarate
-
Homo sapiens cytosine + CO2 + formaldehyde + succinate + H+
-
?

Synonyms

Synonyms Comment Organism
ABH2
-
Homo sapiens
ABH3
-
Homo sapiens