Cloned (Comment) | Organism |
---|---|
quantitative LH gene expression analysis by realtime PCR, genes LH2a and LH2b DNA and amino acid sequence analysis using RT-PCR | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-lysine-[collagen] + 2-oxoglutarate + O2 | Mus musculus | - |
5-hydroxy-L-lysine-[collagen] + succinate + CO2 | - |
? | |
additional information | Mus musculus | 1,25(OH)2D3 directly regulates collagen cross-linking in MC3T3-E1 cells likely by upregulating gene expression of specific lysyl hydroxylase and lysine oxidase enzymes, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MC3T3-E1 cell | a clonal osteoblast-like calvarial cell line | Mus musculus | - |
osteoblast | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-lysine-[collagen] + 2-oxoglutarate + O2 | - |
Mus musculus | 5-hydroxy-L-lysine-[collagen] + succinate + CO2 | - |
? | |
additional information | 1,25(OH)2D3 directly regulates collagen cross-linking in MC3T3-E1 cells likely by upregulating gene expression of specific lysyl hydroxylase and lysine oxidase enzymes, overview | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
lysyl hydroxylase | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | gene expressions of isozymes LH1, LH2b and LOXL2 are significantly upregulated by 1,25(OH)2D3, the active form of vitamin D | up |