Protein Variants | Comment | Organism |
---|---|---|
D233A | reduced activity of the recombinant mutant protein | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | contains Fe2+ | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
43746 | - |
x * 43746, calculated from sequence | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N6-methyladenine in DNA + 2-oxoglutarate + O2 | Mus musculus | the enzyme catalyses oxidative demethylation of DNA N6-methyladenine, a prevalent modification in LINE-1 transposons | adenine in DNA + formaldehyde + succinate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P0CB42 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryonic stem cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N6-methyladenine in DNA + 2-oxoglutarate + O2 | - |
Mus musculus | adenine in DNA + formaldehyde + succinate + CO2 | - |
? | |
N6-methyladenine in DNA + 2-oxoglutarate + O2 | the enzyme catalyses oxidative demethylation of DNA N6-methyladenine, a prevalent modification in LINE-1 transposons | Mus musculus | adenine in DNA + formaldehyde + succinate + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 43746, calculated from sequence | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
ALKBH1 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme catalyses oxidative demethylation of DNA N6-methyladenine, a prevalent modification in LINE-1 transposons | Mus musculus |