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Literature summary for extracted from

  • Argandona, M.; Piubeli, F.; Reina-Bueno, M.; Nieto, J.J.; Vargas, C.
    New insights into hydroxyectoine synthesis and its transcriptional regulation in the broad-salt growing halophilic bacterium Chromohalobacter salexigens (2021), Microb. Biotechnol., 14, 1472-1493 .
    View publication on PubMedView publication on EuropePMC


Organism UniProt Comment Textmining
Chromohalobacter salexigens Q1QT61 isoform EctE
Chromohalobacter salexigens Q1RPP0 isoform EctD
Chromohalobacter salexigens DSM 3043 Q1QT61 isoform EctE


Synonyms Comment Organism
Chromohalobacter salexigens
Chromohalobacter salexigens


Organism Comment Expression
Chromohalobacter salexigens expression of isoform EctE is always stress factor RpoS-dependent regardless of the growth phase and osmotic or heat stress conditions additional information
Chromohalobacter salexigens osmoregulated expression of ectD at exponential phase, and the thermoregulated expression of ectD at the stationary phase are dependent on the general stress factor RpoS. AraC-GlxA-like EctZ transcriptional regulator under exponential growth acts as both a transcriptional activator of osmoregulated EctD expression and a repressor of isoform EctE transcription additional information

General Information

General Information Comment Organism
physiological function the ectoine content of single isoform EctE or EctD mutants is similar to that of the wild-type at any condition tested. The ectoine content of the double mutant EctD/EctE is slightly lower at high salinity. At high salinity, the hydroxyectoine level of the EctD mutant is reduced to 56.1% of the wild-type level, whereas that of the ectE mutant is not significatively lower. The double EctD/EctE mutant does not accumulate hydroxyectoine. At high salinity plus high temperature, the hydroxyectoine content of the EctE mutant is reduced to 37.6% of the wild-type level. Growth of the EctD and EctD/EctE mutants is severely impaired at high temperature Chromohalobacter salexigens