Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.11.66 extracted from

  • Sun, Q.; Zhou, D.
    Rice jmjC domain-containing gene JMJ706 encodes H3K9 demethylase required for floral organ development (2008), Proc. Natl. Acad. Sci. USA, 105, 13679-13684.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene JMJ706, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression as GST-fusion protein Oryza sativa

Protein Variants

Protein Variants Comment Organism
additional information a JMJ706 loss-of-function mutation affects floral organogenesis, construction of knockout mutants that show altered content and ratios of methylated histone H3K9, overview Oryza sativa

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus heterochromatin-associated Oryza sativa 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[histone H3]-N6,N6,N6-trimethyl-L-lysine9 + 2 2-oxoglutarate + 2 O2 Oryza sativa
-
[histone H3]-L-lysine9 + 2 succinate + 2 formaldehyde + 2 CO2
-
?
[histone H3]-N6,N6-dimethyl-L-lysine9 + 2 2-oxoglutarate + 2 O2 Oryza sativa
-
[histone H3]-L-lysine9 + 2 succinate + 2 formaldehyde + 2 CO2
-
?

Organism

Organism UniProt Comment Textmining
Oryza sativa Q336N8 gene JMJ706
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme from rice is specific for Lys9 of histone H3 Oryza sativa ?
-
?
[histone H3]-N6,N6,N6-trimethyl-L-lysine9 + 2 2-oxoglutarate + 2 O2
-
Oryza sativa [histone H3]-L-lysine9 + 2 succinate + 2 formaldehyde + 2 CO2
-
?
[histone H3]-N6,N6-dimethyl-L-lysine9 + 2 2-oxoglutarate + 2 O2
-
Oryza sativa [histone H3]-L-lysine9 + 2 succinate + 2 formaldehyde + 2 CO2
-
?

Synonyms

Synonyms Comment Organism
H3K9 demethylase
-
Oryza sativa
More the enzyme belongs to the JMJD2 family jmjC gene famil Oryza sativa

General Information

General Information Comment Organism
physiological function rice JMJ706 encodes a heterochromatin-associated H3K9 demethylase involved in the regulation of flower development in rice. JMJ706 regulates a subset of flower development regulatory genes Oryza sativa