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Literature summary for extracted from

  • Resnick, S.M.; Gibson, D.T.
    Oxidation of 6,7-dihydro-5H-benzocycloheptene by bacterial strains expressing naphthalene dioxygenase, biphenyl dioxygenase, and toluene dioxygenase yields homochiral mono-ol or cis-diol enantiomers as major products (1996), Appl. Environ. Microbiol., 62, 1364-1368.
    View publication on PubMedView publication on EuropePMC


Organism UniProt Comment Textmining
Pseudomonas sp.
strain NCIB 9816/11, naphthalene dihydrogenase mutant derived from strain NCIB 9816-4 oxidizing naphthalene to cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6,7-dihydro-5H-benzocycloheptene + NADH + O2 naphthalene dioxygenase activity in cells induced by salicylate Pseudomonas sp. (1R,2S)-cis-dihydroxybenzocycloheptane + NAD+ enantiomeric excess greater than 98% ?