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Literature summary for extracted from

  • Whited, G.M.; Downie, J.C.; Hudlicky, T.; Fearnley, S.P.; Dudding, t.C.; Olivo, H.F.; Parker, D.
    Oxidation of 2-methoxynaphthalene by toluene, naphthalene and biphenyl dioxygenases: structure and absolute stereochemistry of metabolites (1994), Bioorg. Med. chem., 2, 727-734.
    View publication on PubMed


Organism UniProt Comment Textmining
Pseudomonas sp.
strain NCIB 9816/11, naphthalene dihydrogenase mutant derived from strain NCIB 9816-4 oxidizing naphthalene to cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-methoxynaphthalene + NADH + O2 naphtalene dioxygenase activity in whole cells and activity in E. coli cells expressing naphtalene dioxygenase Pseudomonas sp. (1R,2S)-dihydroxy-7-methoxy-1,2-dihydronaphthalene + NAD+ minor product (1R,2S)-dihydroxy-6-methoxy-1,2-dihydronaphthalene ?