Protein Variants | Comment | Organism |
---|---|---|
D362A | mutation in alpha subunit of terminal dioxygenase ISPNAP, no activity with naphthalene, biphenyl and phenanthrene | Pseudomonas sp. |
F202L | mutation in alpha subunit of terminal dioxygenase ISPNAP, no activity with naphthalene, biphenyl and phenanthrene | Pseudomonas sp. |
F202V | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
F352L | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type, major product of biphenyl oxidation: biphenyl-3,4-dihydrodiol instead of biphenyl-2,3-dihydrodiol | Pseudomonas sp. |
F352V | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type, product of biphenyl oxidation: 96% biphenyl-3,4-dihydrodiol instead of biphenyl-2,3-dihydrodiol | Pseudomonas sp. |
M366W | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
N201A | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene as wild-type, very weak activity with biphenyl | Pseudomonas sp. |
N201Q | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
N201S | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
T351N | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
T351R | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
T351S | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
V260A | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
V260L | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
V260N | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
W316A | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
W358A | mutation in alpha subunit of terminal dioxygenase ISPNAP, very low activity with naphthalene and biphenyl | Pseudomonas sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas sp. | - |
strain NCIB 9816/11, naphthalene dihydrogenase mutant derived from strain NCIB 9816-4 oxidizing naphthalene to cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene | - |