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Literature summary for 1.14.12.25 extracted from

  • DeFrank, J.; Ribbons, D.
    p-Cymene pathway in Pseudomonas putida: initial reactions (1977), J. Bacteriol., 129, 1356-1364.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
p-cumate + NADH + H+ + O2 Pseudomonas putida
-
2,3-dihydroxy-2,3-dihydro-p-cumate + NAD+ the substrate for the ring cleavage of 2,3-dihydroxy-p-cumate is formed from p-cumate in two reactions via a dihydrodiol intermediate (2,3-dihydroxy-4-isopropylcyclohexa-4,6-dienoate). Both hydroxyl atoms of the dihydrodiol are derived from the same molecule of 02 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas putida
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
p-cumate + NADH + H+ + O2
-
Pseudomonas putida 2,3-dihydroxy-2,3-dihydro-p-cumate + NAD+ the substrate for the ring cleavage of 2,3-dihydroxy-p-cumate is formed from p-cumate in two reactions via a dihydrodiol intermediate (2,3-dihydroxy-4-isopropylcyclohexa-4,6-dienoate). Both hydroxyl atoms of the dihydrodiol are derived from the same molecule of 02 ?

General Information

General Information Comment Organism
physiological function a mutant of Pseudomonas putida, which is unable to grow with p-cumate, accumulates 2,3-dihydroxy-4-isoproplycyclohexa-4,6-dienoate. Both hydroxyl atoms of the dihydrodiol are derived from the same molecule of 02 Pseudomonas putida