Literature summary for 1.14.12.26 extracted from

Beil, S.; Happe, B.; Timmis, K.N.; Pieper, D.H.
Genetic and biochemical characterization of the broad spectrum chlorobenzene dioxygenase from Burkholderia sp. strain PS12 - dechlorination of 1,2,4,5-tetrachlorobenzene (1997), Eur. J. Biochem., 247, 190-199 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli	Cupriavidus sp. PS12

Organism

Organism	UniProt	Comment	Textmining
Cupriavidus sp. PS12	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1,2,4,5-tetrachlorobenzene + NADH + H+ + O2	the enzyme dioxygenolytically attacks a chlorosubstituted carbon atom of Cl4-benzene, thereby forming an unstable diol intermediate which spontaneously rearomatizes with concomitant chloride elimination to the corresponding 3,4,6-trichlorocatechol (Cl3-catechol)	Cupriavidus sp. PS12	? + NAD+	-	?

Synonyms

Synonyms	Comment	Organism
TecA	-	Cupriavidus sp. PS12

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Release 2023.1 (January 2023)