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Literature summary for 1.14.13.149 extracted from

  • Lightly, T.; Frejuk, K.; Groleau, M.; Chiarelli, L.; Ras, C.; Buroni, S.; Deziel, E.; Sorensen, J.; Cardona, S.
    Phenylacetyl coenzyme a, not phenylacetic acid, attenuates CepIR-regulated virulence in Burkholderia cenocepacia (2019), Appl. Environ. Microbiol., 85, e01594 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Burkholderia cenocepacia A0A1V6KKT5 and A0A125H2T4 and A0A2N9CKU5 and A0A088UAI6 and A0A7G6UV70 A0A1V6KKT5 i.e. subunit PaaA, A0A125H2T4 i.e. subunit PaaB, A0A2N9CKU5 i.e. subunit PaaC, A0A088UAI6 i.e. subunit PaaD, and A0A7G6UV70 i.e. subunit PaaE
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Synonyms

Synonyms Comment Organism
PaaABCDE
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Burkholderia cenocepacia

General Information

General Information Comment Organism
physiological function loss of PaaABCDE decreases virulence. Deletion of either ligase PaaK or PaaABCDE leads to higher levels of released phenylacetic acid but no differences in levels of internal accumulation compared to the wild-type level. Removal of PaaABCDE in a LuxIR-like quorum sensing system CepR mutant does not impact its attenuated phenotype Burkholderia cenocepacia