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Literature summary for 1.14.13.20 extracted from

  • Chris Felshia, S.; AshwinKarthick, N.; Thilagam, R.; Gnanamani, A.
    Elucidation of 2,4-dichlorophenol degradation by Bacillus licheniformis strain SL10 (2020), Environ. Technol., 41, 366-377 .
    View publication on PubMed

Application

Application Comment Organism
environmental protection 2,4-dichlorophenoxy acetic acid (2,4-D) is of particular concern, as this synthetic auxin has been the most utilized herbicide in the past 50 years. It is prevalent in agricultural fields and has been widely applied in cereal crops to control broadleaved weeds. It inhibits the growth of leaf weeds by accumulating in the plant root. 2,4-D accumulated crops, on consumption, result in gastrointestinal haemorrhage, direct myocardial toxicity, CNS depression, renal failure, and other disorders. The bacterium Bacillus licheniformis strain SL10 finds potential application in the remediation of 2,4-dichlorophenol Bacillus licheniformis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,4-dichlorophenol + NADPH + H+ + O2 Bacillus licheniformis
-
3,5-dichlorocatechol + NADP+ + H2O
-
?
2,4-dichlorophenol + NADPH + H+ + O2 Bacillus licheniformis MTCC 25059
-
3,5-dichlorocatechol + NADP+ + H2O
-
?
2,4-dichlorophenol + NADPH + H+ + O2 Bacillus licheniformis SL10
-
3,5-dichlorocatechol + NADP+ + H2O
-
?

Organism

Organism UniProt Comment Textmining
Bacillus licheniformis
-
-
-
Bacillus licheniformis MTCC 25059
-
-
-
Bacillus licheniformis SL10
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,4-dichlorophenol + NADPH + H+ + O2
-
Bacillus licheniformis 3,5-dichlorocatechol + NADP+ + H2O
-
?
2,4-dichlorophenol + NADPH + H+ + O2
-
Bacillus licheniformis MTCC 25059 3,5-dichlorocatechol + NADP+ + H2O
-
?
2,4-dichlorophenol + NADPH + H+ + O2
-
Bacillus licheniformis SL10 3,5-dichlorocatechol + NADP+ + H2O
-
?

Synonyms

Synonyms Comment Organism
phenol hydroxylase
-
Bacillus licheniformis

Cofactor

Cofactor Comment Organism Structure
FAD
-
Bacillus licheniformis
NADPH
-
Bacillus licheniformis

General Information

General Information Comment Organism
metabolism the enzyme is involved in the catabolism of 2,4-dichlorophenol, pathways, overview Bacillus licheniformis
physiological function degradation of 2,4-dichlorophenol (2,4-DCP) by phenol adapted bacterium Bacillus licheniformis strain SL10 (MTCC 25059) at a relatively fast rate. The organism exhibits tolerance to 150 ppm of 2,4-DCP and shows a linear relationship between the growth and substrate concentration, the inhibitory concentration is 55.74 mg/l, kinetics, overview. The degradation efficiency of the organism is 74% under optimum conditions but increases to 97% when the growth medium contains nil sodium chloride. The organism follows a meta-cleavage pathway while degrading 2,4-DCP Bacillus licheniformis