Literature summary for 1.14.13.22 extracted from

Hu, Y.; Xu, W.; Hui, C.; Xu, J.; Huang, M.; Lin, X.; Wu, Q.
The mutagenesis of a single site for enhancing or reversing the enantio- or regiopreference of cyclohexanone monooxygenases (2020), Chem. Commun. (Camb.), 56, 9356-9359 .

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Protein Variants

Protein Variants	Comment	Organism
F277I	mutation reverses stereoselectivity of wild-type	Acinetobacter johnsonii
F277P	mutation reverses stereoselectivity of wild-type	Acinetobacter johnsonii
F277V	mutation reverses stereoselectivity of wild-type	Acinetobacter johnsonii
F277W	mutation enhances stereoselectivity of wild-type	Acinetobacter johnsonii

Organism

Organism	UniProt	Comment	Textmining
Acinetobacter johnsonii	P12015	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-phenylcyclohexanone + NADPH + H+ + O2	-	Acinetobacter johnsonii	1-oxa-2-oxo-3-phenylcycloheptane + NADP+ + H2O	-	?
3-phenylcyclobutanone+ NADPH + H+ + O2	-	Acinetobacter johnsonii	3-phenyloxolan-2-one + NADP+ + H2O	-	?
3-phenylcyclohexanone + NADPH + H+ + O2	-	Acinetobacter johnsonii	1-oxa-2-oxo-4-phenylcycloheptane + NADP+ + H2O	-	?
3-phenylcyclopentanone + NADPH + H+ + O2	-	Acinetobacter johnsonii	4-phenyloxan-2-one + NADP+ + H2O	-	?

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Release 2023.1 (January 2023)