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Literature summary for 1.14.13.35 extracted from
- New pathway for the biodegradation of indole in Aspergillus niger (1990), Appl. Environ. Microbiol., 56, 275-280.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| indole | 0.02% induces the enzyme 516fold | Aspergillus niger |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| anthranilate + NADPH + O2 | Aspergillus niger | metabolism of indole | 2,3-dihydroxybenzoate + NADP+ + NH3 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus niger | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.05 | - |
in cell extracts grown on glucose | Aspergillus niger |
| 25.8 | - |
in cell extracts grown on glucose plus indole | Aspergillus niger |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| anthranilate + NADPH + O2 | - |
Aspergillus niger | 2,3-dihydroxybenzoate + NADP+ + NH3 | - |
? | |
| anthranilate + NADPH + O2 | metabolism of indole | Aspergillus niger | 2,3-dihydroxybenzoate + NADP+ + NH3 | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
assay at | Aspergillus niger |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Aspergillus niger | |
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Release 2023.1 (January 2023)
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