Activating Compound | Comment | Organism | Structure |
---|---|---|---|
n-decyl-beta-D-maltoside | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus | |
n-dodecyl-beta-D-maltoside | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus | |
n-dodecyl-N,N-dimethylamine-n-oxide | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus | |
n-nonyl-beta-D-glucoside | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus | |
n-octyl-beta-D-glucoside | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus | |
n-octyl-beta-D-thioglucoside | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus |
Cloned (Comment) | Organism |
---|---|
expression of N-terminally His6-tagged truncation mutant in Escherichia coli as soluble enzyme, and expression of the mutant in Spodoptera frugiperda Sf9 insect cells | Oryctolagus cuniculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | C-terminal truncation of 26 amino acids and and a double Ser substitutio of isozyme FMO2 enhances the enzyme solubility and reduce hydrophobicity required for efficient enzyme crystallization, overview | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
n-decyl-beta-D-maltoside | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus | |
n-dodecyl-beta-D-maltoside | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus | |
n-dodecyl-N,N-dimethylamine-n-oxide | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus | |
n-nonyl-beta-D-glucoside | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus | |
n-octyl-beta-D-glucoside | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus | |
n-octyl-beta-D-thioglucoside | 1%, activates at pH 7.5-8.5, inhibits at pH 9.5, mutant and wild-type enzymes | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | associated | Oryctolagus cuniculus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Oryctolagus cuniculus | the enzyme is involved in oxidative metabolism of drugs and other chemicals | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | P17635 | isozyme FMO2 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is involved in oxidative metabolism of drugs and other chemicals | Oryctolagus cuniculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FMO | - |
Oryctolagus cuniculus |