BRENDA - Enzyme Database show
show all sequences of 1.14.14.1

Amino acids in SRS1 and SRS6 are critical for furanocoumarin metabolism by CYP6B1v1, a cytochrome P450 monooxygenase

Chen, J.S.; Berenbaum, M.R.; Schuler, M.A.; Insect Mol. Biol. 11, 175-186 (2002)

Data extracted from this reference:

Engineering
Amino acid exchange
Commentary
Organism
F116A
no enzymatic activity
Papilio polyxenes
F116C
no enzymatic activity
Papilio polyxenes
F116H
no enzymatic activity
Papilio polyxenes
F116I
no enzymatic activity
Papilio polyxenes
F116L
no enzymatic activity
Papilio polyxenes
F116L/F484L
no enzymatic activity
Papilio polyxenes
F116L/F484Y
no enzymatic activity
Papilio polyxenes
F116S
no enzymatic activity
Papilio polyxenes
F116V
no enzymatic activity
Papilio polyxenes
F116W
some enzymatic activity against bergapten, xanthotoxin
Papilio polyxenes
F116Y
reduced enzymatic activity
Papilio polyxenes
F116Y/F484H
no enzymatic activity
Papilio polyxenes
F116Y/F484Y
no enzymatic activity
Papilio polyxenes
F206L
no enzymatic activity
Papilio polyxenes
F484C
no enzymatic activity
Papilio polyxenes
F484D
no enzymatic activity
Papilio polyxenes
F484H
no enzymatic activity
Papilio polyxenes
F484L
no enzymatic activity
Papilio polyxenes
F484S
no enzymatic activity
Papilio polyxenes
F484V
no enzymatic activity
Papilio polyxenes
F484W
no enzymatic activity
Papilio polyxenes
F484Y
no enzymatic activity
Papilio polyxenes
H117A
no enzymatic activity
Papilio polyxenes
H117F
no enzymatic activity
Papilio polyxenes
H117L/F484Y
no enzymatic activity
Papilio polyxenes
H117V
no enzymatic activity
Papilio polyxenes
H117Y
no enzymatic activity
Papilio polyxenes
H204L
activity similar to wild-type
Papilio polyxenes
V368A
activity similar to wild-type; no enzymatic activity
Papilio polyxenes
V368F
no enzymatic activity
Papilio polyxenes
V368L
activity similar to wild-type; no enzymatic activity
Papilio polyxenes
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Papilio polyxenes
Q04552
black swallowtail caterpillar
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-hydroxy-1-(4-hydroxyphenyl)guanidine + [reduced NADPH-hemoprotein reductase] + O2
-
658917
Papilio polyxenes
?
-
-
-
?
bergapten + [reduced NADPH-hemoprotein reductase] + O2
-
658917
Papilio polyxenes
? + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
isopimpinellin + [reduced NADPH-hemoprotein reductase] + O2
-
658917
Papilio polyxenes
? + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
psoralen + [reduced NADPH-hemoprotein reductase] + O2
-
658917
Papilio polyxenes
? + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
xanthotoxin + reduced flavoprotein + O2
-
658917
Papilio polyxenes
? + oxidized flavoprotein + H2O
-
-
-
?
Cofactor
Cofactor
Commentary
Organism
Structure
cytochrome P450
-
Papilio polyxenes
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
cytochrome P450
-
Papilio polyxenes
Engineering (protein specific)
Amino acid exchange
Commentary
Organism
F116A
no enzymatic activity
Papilio polyxenes
F116C
no enzymatic activity
Papilio polyxenes
F116H
no enzymatic activity
Papilio polyxenes
F116I
no enzymatic activity
Papilio polyxenes
F116L
no enzymatic activity
Papilio polyxenes
F116L/F484L
no enzymatic activity
Papilio polyxenes
F116L/F484Y
no enzymatic activity
Papilio polyxenes
F116S
no enzymatic activity
Papilio polyxenes
F116V
no enzymatic activity
Papilio polyxenes
F116W
some enzymatic activity against bergapten, xanthotoxin
Papilio polyxenes
F116Y
reduced enzymatic activity
Papilio polyxenes
F116Y/F484H
no enzymatic activity
Papilio polyxenes
F116Y/F484Y
no enzymatic activity
Papilio polyxenes
F206L
no enzymatic activity
Papilio polyxenes
F484C
no enzymatic activity
Papilio polyxenes
F484D
no enzymatic activity
Papilio polyxenes
F484H
no enzymatic activity
Papilio polyxenes
F484L
no enzymatic activity
Papilio polyxenes
F484S
no enzymatic activity
Papilio polyxenes
F484V
no enzymatic activity
Papilio polyxenes
F484W
no enzymatic activity
Papilio polyxenes
F484Y
no enzymatic activity
Papilio polyxenes
H117A
no enzymatic activity
Papilio polyxenes
H117F
no enzymatic activity
Papilio polyxenes
H117L/F484Y
no enzymatic activity
Papilio polyxenes
H117V
no enzymatic activity
Papilio polyxenes
H117Y
no enzymatic activity
Papilio polyxenes
H204L
activity similar to wild-type
Papilio polyxenes
V368A
activity similar to wild-type; no enzymatic activity
Papilio polyxenes
V368F
no enzymatic activity
Papilio polyxenes
V368L
activity similar to wild-type; no enzymatic activity
Papilio polyxenes
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-hydroxy-1-(4-hydroxyphenyl)guanidine + [reduced NADPH-hemoprotein reductase] + O2
-
658917
Papilio polyxenes
?
-
-
-
?
bergapten + [reduced NADPH-hemoprotein reductase] + O2
-
658917
Papilio polyxenes
? + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
isopimpinellin + [reduced NADPH-hemoprotein reductase] + O2
-
658917
Papilio polyxenes
? + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
psoralen + [reduced NADPH-hemoprotein reductase] + O2
-
658917
Papilio polyxenes
? + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
xanthotoxin + reduced flavoprotein + O2
-
658917
Papilio polyxenes
? + oxidized flavoprotein + H2O
-
-
-
?
Other publictions for EC 1.14.14.1
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
744431
Matowane
In silico analysis of cytochr ...
Sporothrix schenckii, Sporothrix schenckii ATCC 58251
Biochim. Biophys. Acta
1866
166-177
2018
-
-
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1
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-
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6
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2
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1
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1
1
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-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
746324
Hasegawa
Cytochrome P450 monooxygenase ...
Homo sapiens
Proc. Natl. Acad. Sci. USA
114
E7545-E7553
2017
-
1
-
-
-
-
-
-
-
-
-
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3
-
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1
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-
-
1
1
-
-
-
744184
Kolrep
Differences in metabolism of ...
Homo sapiens, Rattus norvegicus
Arch. Toxicol.
90
2025-2036
2016
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-
2
-
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2
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5
-
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3
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3
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3
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3
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-
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2
3
-
-
-
745019
Wriessnegger
Enhancing cytochrome P450-med ...
Homo sapiens
Fungal Genet. Biol.
89
114-125
2016
1
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
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-
1
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1
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1
1
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-
744697
Yin
Unusually broad substrate pro ...
Labrenzia aggregata, Labrenzia aggregata DSM 13394
ChemBioChem
15
2443-2449
2014
-
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
19
1
-
-
-
-
-
-
-
5
-
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-
1
5
-
-
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-
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-
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19
1
-
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745417
Lee
Production of bioactive hydro ...
Saccharothrix espanaensis
J. Biotechnol.
176
11-17
2014
-
1
1
-
-
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-
-
-
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1
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7
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1
1
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7
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745559
Tosstorff
-
Mediated electron transfer wi ...
Bacillus megaterium, Bacillus megaterium DSM 32
J. Mol. Catal. B
108
51-58
2014
-
1
1
-
1
-
-
-
-
-
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-
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2
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2
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1
1
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1
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-
2
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-
-
-
-
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746534
Lavado
Evaluation of the stereoselec ...
Homo sapiens
Toxicol. Lett.
226
192-197
2014
-
1
-
-
-
-
1
8
-
-
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-
2
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1
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5
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1
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1
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8
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1
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5
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-
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-
-
-
726736
Syed
CYP63A2, a catalytically versa ...
Phanerochaete chrysosporium
Appl. Environ. Microbiol.
79
2692-2702
2013
-
-
1
-
-
-
-
-
-
-
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-
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2
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6
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1
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6
-
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728729
Syed
Rational engineering of the fu ...
Phanerochaete chrysosporium
Protein Eng.
26
553-557
2013
-
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1
-
5
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1
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5
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2
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726823
Wang
The involvement of cytochrome ...
Drosophila melanogaster
Arch. Insect Biochem. Physiol.
79
264-275
2012
1
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1
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4
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1
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1
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1
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726832
Ide
Molecular identification and f ...
Postia placenta, Postia placenta MAD-698
Arch. Microbiol.
194
243-253
2012
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1
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6
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6
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727589
Misra
Characterization of cytochrome ...
Artemisia annua
Gene
510
193-201
2012
-
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1
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1
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3
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3
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5
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1
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1
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3
-
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5
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712253
Zocher
Structural fine-tuning of a mu ...
Streptomyces thioluteus
J. Am. Chem. Soc.
133
2292-2302
2011
-
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1
1
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1
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1
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1
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1
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2
1
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1
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1
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1
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713071
Brignac-Huber
Organization of NADPH-cytochro ...
Oryctolagus cuniculus
Mol. Pharmacol.
79
549-557
2011
-
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2
1
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2
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726753
Schallmey
Characterization of cytochrome ...
Thermobifida fusca
Appl. Microbiol. Biotechnol.
89
1475-1485
2011
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1
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1
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1
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13
1
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13
1
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1
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728324
Lah
The versatility of the fungal ...
Curvularia lunata
Mol. Microbiol.
81
1374-1389
2011
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1
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5
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1
1
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701865
Zhang
Sequence analysis and heterolo ...
Rhodococcus sp.
Appl. Microbiol. Biotechnol.
85
615-624
2010
-
1
1
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-
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1
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1
1
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4
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1
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7
-
1
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1
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3
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1
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1
1
3
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1
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1
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1
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7
-
1
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1
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1
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703483
Liu
Human cytochrome P450 2E1 and ...
Homo sapiens
Environ. Mol. Mutagen.
51
23-30
2010
-
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1
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1
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3
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1
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1
1
1
1
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704714
Chen
Scanning chimeragenesis: the a ...
Bacillus megaterium
J. Biol. Inorg. Chem.
15
159-174
2010
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1
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7
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1
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710821
Nayeem
Modulation by salt intake of t ...
Homo sapiens, Mus musculus, Rattus norvegicus
Am. J. Physiol. Regul. Integr. Comp. Physiol.
299
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2010
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3
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21
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3
3
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710938
Lamb
Streptomyces coelicolor A3(2) ...
Streptomyces coelicolor, Streptomyces coelicolor A3(2)
Appl. Environ. Microbiol.
76
1975-1980
2010
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11
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1
1
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711114
Flueck
Reduction in hepatic drug meta ...
Homo sapiens
Biochem. Biophys. Res. Commun.
401
149-153
2010
1
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1
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2
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1
1
1
1
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711488
Zhang
Improved expression of recombi ...
Rhodococcus sp.
Bioprocess Biosyst. Eng.
33
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2010
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1
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6
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1
1
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1
1
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711544
Liu
Engineering cytochrome P450 mo ...
Rhodococcus ruber
Biotechnol. Lett.
32
841-845
2010
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1
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3
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3
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1
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1
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712306
Tischler
StyA1 and StyA2B from Rhodococ ...
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J. Bacteriol.
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5220-5227
2010
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4
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1
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5
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13
1
1
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-
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1
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713083
Platt
Fruits and vegetables protect ...
Homo sapiens
Mutat. Res.
703
90-98
2010
-
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1
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1
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1
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24
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3
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1
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1
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-
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698017
Liu
Aromatase (P450arom) and 11bet ...
Monopterus albus
Fish Physiol. Biochem.
35
511-518
2009
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1
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1
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4
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4
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4
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1
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-
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701804
Subramanian
Role of P450 monooxygenases in ...
Phanerochaete chrysosporium, Phanerochaete chrysosporium BKM-F-1767
Appl. Environ. Microbiol.
75
5570-5580
2009
-
-
-
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1
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11
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1
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-
-
2
-
-
-
-
-
-
-
-
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2
1
1
2
-
-
703164
Pekthong
Effects of Andrographis panicu ...
Homo sapiens, Rattus norvegicus
Chem. Biol. Interact.
179
247-255
2009
-
-
-
-
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2
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10
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8
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8
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6
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12
-
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8
-
-
-
-
-
-
-
-
-
4
-
-
11
-
-
703178
Robin
Engineering and improvement of ...
synthetic construct
Chem. Commun. (Camb. )
0
2478-2480
2009
1
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1
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-
-
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-
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2
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1
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1
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1
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1
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1
1
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1
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-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
704174
Wright
A suite of activity-based prob ...
Homo sapiens
J. Am. Chem. Soc.
131
10692-10700
2009
1
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1
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4
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1
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3
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1
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1
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1
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1
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1
1
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-
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2
4
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1
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1
-
-
1
-
-
-
-
-
-
-
-
-
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1
1
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-
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704856
Tam
Actions of ethnobotanically se ...
Homo sapiens
J. Ethnopharmacol.
126
119-126
2009
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1
1
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8
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9
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1
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7
7
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18
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9
-
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-
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704859
Hardstone
Multiplicative interaction bet ...
Culex quinquefasciatus
J. Evol. Biol.
22
416-423
2009
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1
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-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
705804
Acharya
Hepatic CYP3A suppression by h ...
Rattus norvegicus
Mol. Pharmacol.
76
503-515
2009
-
-
-
-
-
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1
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1
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1
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1
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1
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1
-
-
-
-
-
-
-
-
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-
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1
-
-
1
-
-
706195
Page
Metabolism of sulphonated anth ...
Apium graveolens, Rheum rhaponticum, Zea mays
Plant Cell Rep.
28
1725-1735
2009
-
1
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-
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3
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7
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6
34
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15
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1
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3
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6
34
-
15
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
706309
Pan
Cytochrome P450 monooxygenases ...
Arabidopsis thaliana
Plant Physiol.
150
858-878
2009
-
-
-
-
-
-
-
-
-
-
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-
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2
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-
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1
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-
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-
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1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
706777
Furuya
Phylogenetic analysis of Bacil ...
Bacillus cereus
Steroids
74
906-912
2009
-
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1
-
-
-
-
-
-
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-
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10
-
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8
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1
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5
3
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-
-
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-
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-
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-
-
-
-
-
-
-
-
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8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
706825
Zhang
Sequencing and characterizatio ...
Neovison vison
Toxicol. Appl. Pharmacol.
234
306-313
2009
-
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1
-
-
-
-
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1
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2
-
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7
-
-
-
-
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2
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2
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2
-
2
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-
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3
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
706841
Beedanagari
Resveratrol inhibits dioxin-in ...
Homo sapiens
Toxicol. Sci.
110
61-67
2009
-
-
-
-
-
-
-
-
1
-
-
-
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2
-
-
-
-
-
2
-
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-
-
-
-
-
-
-
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-
-
1
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-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
684718
Kranendonk
Impairment of human CYP1A2-med ...
Homo sapiens
Arch. Biochem. Biophys.
475
93-99
2008
-
-
1
-
-
-
1
-
-
-
-
-
-
2
-
-
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-
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1
-
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2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
686232
Henczova
Effects of Cu(2+) and Pb(2+) o ...
Cyprinus carpio, Hypophthalmichthys molitrix, Silurus glanis
Comp. Biochem. Physiol. C
148
53-60
2008
-
-
-
-
-
-
6
-
3
3
-
-
-
6
-
-
3
-
-
4
3
-
-
-
3
-
-
-
3
-
-
3
-
-
-
-
-
-
3
-
-
-
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6
-
-
3
3
-
-
-
-
-
3
-
4
3
-
-
-
3
-
-
-
3
-
-
-
-
-
-
-
-
-
693835
Panicco
P450 versus P420: Correlation ...
Bacillus megaterium
J. Phys. Chem. B
112
14063
2008
-
1
-
-
-
-
-
-
-
-
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2
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-
-
-
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-
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1
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
695046
Branco
Anchoring effects in a wide bi ...
Bacillus megaterium
Proteins
73
597-607
2008
-
-
1
1
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
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13
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
701574
Pachecka
Cytochrome P450 polymorphism-- ...
Homo sapiens
Acta Pol. Pharm.
65
303-306
2008
-
-
-
-
-
-
-
-
2
1
-
-
-
5
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
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-
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4
-
-
-
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2
1
-
-
-
-
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-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
701835
Dietrich
Cloning, expression and charac ...
Bacillus licheniformis, Bacillus licheniformis DSM 13
Appl. Microbiol. Biotechnol.
79
931-940
2008
-
-
1
-
-
-
1
9
-
-
1
-
-
4
-
-
1
-
-
-
-
-
29
1
-
-
1
9
1
-
1
3
-
-
-
-
-
1
3
-
-
-
-
1
-
9
-
-
1
-
-
-
-
1
-
-
-
-
29
1
-
-
1
9
1
-
1
-
-
-
-
-
-
-
706089
Diczfalusy
4Beta-hydroxycholesterol is a ...
Homo sapiens
Pharmacogenet. Genomics
18
201-208
2008
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
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-
-
-
1
-
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1
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-
-
-
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1
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-
-
1
-
1
-
-
-
-
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-
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-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
706823
Leoni
The participation of human hep ...
Homo sapiens
Toxicol. Appl. Pharmacol.
233
343-352
2008
-
-
1
-
-
-
5
12
1
-
-
-
-
7
-
-
-
-
-
2
-
-
9
-
-
-
-
-
-
-
-
1
-
-
-
-
-
6
6
-
-
-
-
12
-
12
6
-
-
-
-
-
-
-
-
7
-
-
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672654
Vatsyayan
Broad substrate cytochrome P45 ...
Aspergillus terreus, Aspergillus terreus MTCC 6324
Biores. Technol.
99
68-75
2007
-
-
-
-
-
-
-
-
3
1
1
-
-
7
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
3
1
1
-
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671286
Henczova
Detection of toxic effects of ...
Cyprinus carpio, Hypophthalmichthys molitrix, Silurus glanis
Anal. Bioanal. Chem.
385
652-659
2006
5
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3
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3
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9
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6
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15
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9
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5
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3
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3
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3
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9
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6
15
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9
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3
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3
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671538
Liu
Cloning, expression, and chara ...
Rhodococcus ruber
Appl. Microbiol. Biotechnol.
72
876-882
2006
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1
1
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1
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1
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9
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1
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4
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1
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1
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9
1
1
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2
1
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-
672648
Roccatano
Toward understanding the inact ...
Bacillus megaterium
Biopolymers
83
467-476
2006
-
1
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2
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1
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2
2
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1
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-
673083
Haarmann
Identification of the cytochro ...
Claviceps purpurea, Claviceps purpurea P1
Chembiochem
7
645-652
2006
-
-
1
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1
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1
1
4
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3
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8
1
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1
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1
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1
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4
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8
1
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-
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-
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-
673315
Arun
Subcellular/tissue distributio ...
Macrobrachium lamarrei, Macrobrachium malcolmsonii
Ecotoxicology
15
341-346
2006
2
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6
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2
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5
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2
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8
2
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2
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2
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6
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2
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8
2
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2
-
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-
-
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-
-
-
-
-
-
-
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-
673780
Chan
Induction and inhibition of cy ...
Rattus norvegicus
Food Chem. Toxicol.
44
2047-2057
2006
1
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1
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1
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2
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3
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3
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1
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-
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-
-
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673817
Alvarez
The crtS gene of Xanthophyllom ...
Xanthophyllomyces dendrorhous
Fungal Genet. Biol.
43
261-272
2006
-
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1
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1
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1
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2
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4
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2
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-
-
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-
-
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674671
Hirao
Effects of restricted feeding ...
Rattus norvegicus
J. Biol. Chem.
281
3165-3171
2006
-
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1
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1
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1
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2
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2
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6
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1
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2
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6
-
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-
-
-
-
-
-
-
-
674753
Zhao
Structure of microsomal cytoch ...
Oryctolagus cuniculus
J. Biol. Chem.
281
5973-5981
2006
-
-
1
1
1
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1
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1
1
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1
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1
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2
1
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1
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1
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1
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1
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1
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2
1
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-
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-
-
-
-
674972
Eiben
Preparative use of isolated CY ...
Bacillus megaterium, Bacillus subtilis
J. Biotechnol.
124
662-669
2006
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2
2
1
10
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1
11
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2
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2
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2
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5
2
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3
20
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9
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2
2
9
1
10
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1
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11
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2
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2
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5
2
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3
20
-
-
-
-
-
-
-
-
-
-
675036
Zeng
Toxicity of aflatoxin B1 to He ...
Helicoverpa zea
J. Chem. Ecol.
32
1459-1471
2006
1
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1
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1
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8
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1
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1
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1
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2
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-
-
-
-
-
-
675947
Ito
Expression of cytochrome P-450 ...
Homo sapiens, Rattus norvegicus
Mol. Cell. Biochem.
284
141-148
2006
-
-
-
-
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2
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4
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4
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2
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8
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2
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8
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6
2
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-
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676430
Zhu
Elongated uppermost internode ...
Oryza sativa
Plant Cell
18
442-456
2006
-
1
1
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1
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1
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4
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6
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6
-
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-
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-
658959
Hirose
Transgenic rice containing hum ...
Homo sapiens
J. Agric. Food Chem.
53
3461-3467
2005
-
1
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-
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1
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4
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8
1
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1
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1
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8
1
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-
-
-
-
-
-
-
-
-
-
-
-
-
671188
Lee
-
Structural diversification of ...
Streptomyces venezuelae
Adv. Synth. Catal.
347
1369-1378
2005
-
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1
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1
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5
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1
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1
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8
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1
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1
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1
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1
1
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1
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5
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1
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8
-
1
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1
-
-
-
-
-
-
-
-
-
671430
Jungmann
Biocatalytic conversion of ave ...
Streptomyces sp., Streptomyces tubercidicus
Appl. Environ. Microbiol.
71
6968-6976
2005
-
-
2
-
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1
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2
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4
-
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1
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1
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4
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1
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1
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2
2
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1
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1
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1
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4
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
671725
Johnson
Structural diversity of human ...
Homo sapiens
Biochem. Biophys. Res. Commun.
338
331-336
2005
-
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1
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-
-
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2
1
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3
-
2
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1
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6
1
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1
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1
1
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2
1
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3
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6
1
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-
-
-
-
-
-
-
-
-
-
-
-
-
671729
Cashman
Some distinctions between flav ...
Homo sapiens
Biochem. Biophys. Res. Commun.
338
599-604
2005
1
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1
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2
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1
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1
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1
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1
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4
1
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1
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1
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2
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1
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2
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1
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2
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1
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1
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-
-
4
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
672721
Gorinova
-
Cytochrome P450 monooxygenase ...
Homo sapiens, Lolium rigidum, Nicotiana tabacum, Phelipanche ramosa, Rattus norvegicus, Solanum tuberosum, Sorghum sp., Triticum aestivum, Zea mays
Biotechnol. Biotechnol. Equip.
19
105-115
2005
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9
2
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4
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8
-
9
9
-
20
-
9
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7
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2
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20
7
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18
-
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7
9
2
18
-
4
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8
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9
9
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20
-
-
-
-
-
2
-
-
20
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672802
Doddapaneni
Genome-wide structural and evo ...
Phanerochaete chrysosporium, Phanerochaete chrysosporium BKM-F-1767
BMC Genomics
6
92
2005
-
-
1
-
-
-
-
-
-
-
-
12
-
22
-
-
-
-
-
-
-
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12
1
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-
-
-
-
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-
-
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-
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6
-
-
-
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-
-
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-
-
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12
-
-
-
-
-
-
-
-
12
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
676306
Yun
-
Cytochrome P-450 monooxygenase ...
Echinochloa phyllopogon
Pestic. Biochem. Physiol.
83
107-114
2005
1
-
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-
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-
-
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1
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1
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3
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1
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1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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676779
Siminszky
Conversion of nicotine to norn ...
Nicotiana tabacum
Proc. Natl. Acad. Sci. USA
102
14919-14924
2005
-
-
1
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1
-
-
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1
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2
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6
-
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-
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1
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4
-
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4
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3
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4
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2
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4
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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658523
Cashman
Effect of total parenteral nut ...
Rattus norvegicus
Drug Metab. Dispos.
32
222-229
2004
-
1
-
-
-
-
-
-
-
-
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3
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1
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1
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-
-
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-
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1
-
-
-
-
-
-
-
-
-
-
-
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659542
Lentz
Substrate specificity of nativ ...
Bacillus subtilis
J. Biotechnol.
108
41-49
2004
1
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1
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3
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3
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-
-
-
-
-
10
-
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6
-
-
-
-
-
-
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1
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1
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3
1
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6
-
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1
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-
-
-
-
-
-
10
-
-
-
-
6
-
-
-
-
-
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-
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657590
Eschenfeldt
Transformation of fatty acids ...
Candida tropicalis
Appl. Environ. Microbiol.
69
5992-5999
2003
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1
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1
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8
-
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2
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1
2
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-
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4
1
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-
-
-
-
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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660414
Baudry
Molecular docking of substrate ...
Papilio polyxenes
Protein Eng.
16
577-587
2003
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1
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1
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3
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4
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1
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1
1
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3
-
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4
-
-
-
-
-
-
-
-
-
-
-
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-
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658917
Chen
Amino acids in SRS1 and SRS6 a ...
Papilio polyxenes
Insect Mol. Biol.
11
175-186
2002
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31
-
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3
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1
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5
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1
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1
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31
-
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-
-
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-
-
-
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-
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-
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1
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5
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-
-
-
-
-
-
-
-
-
-
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660409
Kikuta
Prostaglandin and leukotriene ...
Oryctolagus cuniculus
Prostaglandins
68-69
345-362
2002
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3
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13
-
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-
-
-
-
-
-
-
-
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-
-
-
-
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-
-
-
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-
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1
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-
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3
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13
-
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-
-
-
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717081
Kobayashi
High-performance liquid chroma ...
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Anal. Biochem.
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342-347
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3
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6
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-
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2
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2
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3
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6
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-
-
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390111
Sevrioukova
Structure of a cytochrome P450 ...
Bacillus megaterium
Proc. Natl. Acad. Sci. USA
96
1863-1868
1999
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1
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-
-
-
-
-
-
-
-
-
-
-
-
-
1
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-
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-
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