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Literature summary for 1.14.14.102 extracted from

  • Zhou, J.; Peng, S.; Lei, N.; Liao, H.; Chen, F.
    Molecular cloning and sequence analysis of (S)-N-methylcoclaurine-3'-hydroxylase gene in Coptis chinensis (2008), Zhong Cao Yao, 39, 419-423.
No PubMed abstract available
Search for more literature for 1.14.14.102

Application

Application Comment Organism
medicine traditional Chinese medicinal plant containing benzylisoquinoline alkaloids as active agents Coptis chinensis

Cloned(Commentary)

Cloned (Comment) Organism
PDR-amplification Coptis chinensis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55040
-
 calculated from amino acids, 488 amino acids, 1680 bp Coptis chinensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 Coptis chinensis
-
 (S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Coptis chinensis B2BF50
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Coptis chinensis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2
-
 Coptis chinensis (S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
(S)-N-methylcoclaurine-3'-hydroxylase
-
 Coptis chinensis
CYP80B3
-
 Coptis chinensis

Cofactor

Cofactor Comment Organism Structure
heme
-
 Coptis chinensis

General Information

General Information Comment Organism
metabolism benzylisoquinoline alkaloid biosynthesis Coptis chinensis