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Literature summary for 1.14.14.11 extracted from

  • Hollmann, F.; Hofstetter, K.; Habicher, T.; Hauer, B.; Schmid, A.
    Direct electrochemical regeneration of monooxygenase subunits for biocatalytic asymmetric epoxidation (2005), J. Am. Chem. Soc., 127, 6540-6541.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
styrene + FADH2 + O2 Pseudomonas sp.
-
(S)-2-phenyloxirane + FAD + H2O
-
?
styrene + FADH2 + O2 Pseudomonas sp. VLB120
-
(S)-2-phenyloxirane + FAD + H2O
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
-
-
Pseudomonas sp. VLB120
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information feasibility of direct electrochemical regeneration of a flavin-dependent monooxygenase for catalysis. Driven only by electrical power, optically pure epoxides are synthesized from corresponding vinyl aromatic compounds. The complicated native enzyme system consisting of three enzymes (StyA, StyB, and an NADH regenerating enzyme) and two cofactors (NADH and FAD) is minimized to the oxygenase component and its flavin prosthetic group Pseudomonas sp. ?
-
?
additional information feasibility of direct electrochemical regeneration of a flavin-dependent monooxygenase for catalysis. Driven only by electrical power, optically pure epoxides are synthesized from corresponding vinyl aromatic compounds. The complicated native enzyme system consisting of three enzymes (StyA, StyB, and an NADH regenerating enzyme) and two cofactors (NADH and FAD) is minimized to the oxygenase component and its flavin prosthetic group Pseudomonas sp. VLB120 ?
-
?
styrene + FADH2 + O2
-
Pseudomonas sp. (S)-2-phenyloxirane + FAD + H2O
-
?
styrene + FADH2 + O2 production of (S)-styrene oxide with 98.5% enantiomeric excess. Direct electrochemical regeneration of FADH2 to substitute for the complex native regeneration cycle including StyB and NADH Pseudomonas sp. (S)-2-phenyloxirane + FAD + H2O
-
?
styrene + FADH2 + O2
-
Pseudomonas sp. VLB120 (S)-2-phenyloxirane + FAD + H2O
-
?
styrene + FADH2 + O2 production of (S)-styrene oxide with 98.5% enantiomeric excess. Direct electrochemical regeneration of FADH2 to substitute for the complex native regeneration cycle including StyB and NADH Pseudomonas sp. VLB120 (S)-2-phenyloxirane + FAD + H2O
-
?

Synonyms

Synonyms Comment Organism
StyA
-
Pseudomonas sp.

Cofactor

Cofactor Comment Organism Structure
FADH2 direct electrochemical regeneration of FADH2 to substitute for the complex native regeneration cycle including StyB and NADH Pseudomonas sp.