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Literature summary for 1.14.14.114 extracted from
- The production of artemisinin precursors in tobacco (2011), Plant Biotechnol. J., 9, 445-454.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | heterologous expression of Artemisia annua amorphadiene synthase and CYP71AV1 in tobacco lead to the accumulation of amorphadiene and artemisinic alcohol, but not artemisinic acid. Additional expression of artemisinic aldehyde DELTA11(13) double-bond reductase DBR2 with or without aldehyde dehydrogenase 1 leads to the additional accumulation dihydroartemisinic alcohol. Results and suggest that amorphane sesquiterpenoid aldehydes are formed, but conditions in the transgenic tobacco cells favour reduction to alcohols rather than oxidation to acids | Artemisia annua |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Artemisia annua | - |
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Release 2023.1 (January 2023)
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