BRENDA - Enzyme Database show
show all sequences of 1.14.14.143

Metabolic engineering of essential oil yield and composition in mint by altering expression of deoxyxylulose phosphate reductoisomerase and menthofuran synthase

Mahmoud, S.S.; Croteau, R.B.; Proc. Natl. Acad. Sci. USA 98, 8915-8920 (2001)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
expression of a homologous antisense version of the menthofuran synthase cDNA, both driven by the CaMV 35S promoter, in Mentha x piperita plants using Agrobacterium tumefaciens strain EHA105 transfection method
Mentha x piperita
Engineering
Amino acid exchange
Commentary
Organism
additional information
expression of a homologous antisense version of the menthofuran synthase cDNA, both driven by the CaMV 35S promoter, in Mentha x piperita plants leads to altered essential oil composition very similar in composition to the DXR46 plant transformed with the sense version of the reductoisomerase, overview
Mentha x piperita
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Mg2+
-
Mentha x piperita
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2
Mentha x piperita
the principal pathway for monoterpene biosynthesis in peppermint, overview
(+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Mentha x piperita
-
cv. Black Mitcham
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
leaf
-
Mentha x piperita
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2
-
286420
Mentha x piperita
(+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2
the principal pathway for monoterpene biosynthesis in peppermint, overview
286420
Mentha x piperita
(+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
Cloned(Commentary) (protein specific)
Commentary
Organism
expression of a homologous antisense version of the menthofuran synthase cDNA, both driven by the CaMV 35S promoter, in Mentha x piperita plants using Agrobacterium tumefaciens strain EHA105 transfection method
Mentha x piperita
Engineering (protein specific)
Amino acid exchange
Commentary
Organism
additional information
expression of a homologous antisense version of the menthofuran synthase cDNA, both driven by the CaMV 35S promoter, in Mentha x piperita plants leads to altered essential oil composition very similar in composition to the DXR46 plant transformed with the sense version of the reductoisomerase, overview
Mentha x piperita
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Mg2+
-
Mentha x piperita
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2
Mentha x piperita
the principal pathway for monoterpene biosynthesis in peppermint, overview
(+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
leaf
-
Mentha x piperita
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2
-
286420
Mentha x piperita
(+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2
the principal pathway for monoterpene biosynthesis in peppermint, overview
286420
Mentha x piperita
(+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
Other publictions for EC 1.14.14.143
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
746129
Nazari
Physiological, biochemical an ...
Mentha x piperita
Plant Physiol. Biochem.
120
202-212
2017
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1
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1
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1
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1
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1
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1
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1
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1
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1
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1
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1
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1
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1
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-
745751
Kumar
-
Development and characterizat ...
Mentha x piperita, no activity in Mentha arvensis cv. Kosi
Mol. Breed.
34
717-724
2014
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1
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1
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1
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2
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3
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1
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1
2
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1
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1
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3
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1
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1
1
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728548
Atsbaha Zebelo
Chrysolina herbacea modulates ...
Mentha aquatica
PLoS ONE
6
e17195
2011
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6
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728665
Lange
Improving peppermint essential ...
Mentha x piperita
Proc. Natl. Acad. Sci. USA
108
16944-16949
2011
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-
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1
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2
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689735
Mahmoud
Menthofuran regulates essentia ...
Mentha x piperita
Proc. Natl. Acad. Sci. USA
100
14481-14486
2003
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1
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1
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1
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3
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1
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1
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1
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3
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286420
Mahmoud
Metabolic engineering of essen ...
Mentha x piperita
Proc. Natl. Acad. Sci. USA
98
8915-8920
2001
-
-
1
-
1
-
-
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1
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1
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3
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1
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1
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684661
Bertea
Demonstration that menthofuran ...
Mentha pulegium, Mentha x piperita
Arch. Biochem. Biophys.
390
279-286
2001
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1
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2
2
1
2
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7
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6
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4
1
1
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1
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4
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1
4
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2
2
1
2
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6
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4
1
1
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1
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