BRENDA - Enzyme Database show
show all sequences of 1.14.14.145

Loblolly pine abietadienol/abietadienal oxidase PtAO (CYP720B1) is a multifunctional, multisubstrate cytochrome P450 monooxygenase

Ro, D.K.; Arimura, G.; Lau, S.Y.; Piers, E.; Bohlmann, J.; Proc. Natl. Acad. Sci. USA 102, 8060-8065 (2005)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
additional information
the enzyme expression is induced upon simulated insect attack using methyl jasmonate treatment of loblolly pine
Pinus taeda
Cloned(Commentary)
Commentary
Organism
CYP720B1, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, de novo diterpenoid formation in metabolically engineered yeast, overview; CYP720B1, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis; CYPA, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis; CYPB, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis; CYPC, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis
Pinus taeda
CYPA1, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis; CYPA2, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis
Picea sitchensis
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
Michaelis–Menten kinetics, recombinant enzyme
Pinus taeda
0.0005
-
abietadienal
pH 7.6, 30°C; pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0006
-
dehydroabietadienal
pH 7.6, 30°C; pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0006
-
isopimaradienal
pH 7.6, 30°C; pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0008
-
abietadienol
pH 7.6, 30°C; pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0015
-
isopimara-7,15-dienol
pH 7.6, 30°C
Pinus taeda
0.0015
-
isopimaradienol
pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0019
-
levopimaradienol
pH 7.6, 30°C; pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0053
-
dehydroabietadienol
pH 7.6, 30°C; pH 7.6, 30°C, recombinant enzyme
Pinus taeda
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
;
Picea sitchensis
-
-
microsome
-
Pinus taeda
-
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
abieta-7,13-dien-18-ol + 2 [reduced NADPH-hemoprotein reductase] + 2 O2
Pinus taeda
-
abieta-7,13-dien-18-oate + 2 [oxidized NADPH-hemoprotein reductase] + 3 H2O
-
-
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
Pinus taeda
PtAO catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine diterpene resin acid biosynthesis
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
additional information
Pinus taeda
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
?
-
-
-
additional information
Picea sitchensis
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
?
-
-
-
additional information
Pinus taeda
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense, the enzyme catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine DRA biosynthesis
?
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Picea sitchensis
Q50EK0
CYPA2; loblolly pine
-
Picea sitchensis
Q50EK1
CYPA1; loblolly pine
-
Pinus taeda
-
loblolly pine
-
Pinus taeda
Q50EK3
CYPD; loblolly pine
-
Pinus taeda
Q50EK4
CYPC; loblolly pine
-
Pinus taeda
Q50EK5
CYPB; loblolly pine
-
Pinus taeda
Q50EK6
; CYPA; loblolly pine
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
additional information
CYP720B1 tissue profiling
Pinus taeda
-
stem
-
Pinus taeda
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
substrate specificity, overview
Pinus taeda
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(13S)-pimara-7,15-dien-18-al + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
(13S)-pimara-7,15-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
abieta-7,13-dien-18-al + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
abieta-7,13-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
abieta-7,13-dien-18-ol + 2 [reduced NADPH-hemoprotein reductase] + 2 O2
-
676795
Pinus taeda
abieta-7,13-dien-18-oate + 2 [oxidized NADPH-hemoprotein reductase] + 3 H2O
-
-
-
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
PtAO catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine diterpene resin acid biosynthesis
676795
Pinus taeda
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
abietadienal + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
abietadienoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
abietadienol + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
abietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
dehydroabietadienal + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
dehydroabietadienoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
dehydroabietadienal + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
dehydroabietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
dehydroabietadienol + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
dehydroabietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
dehydroabietadienol + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
dehydroabietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
isopimara-7,15-dienal + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
isopimara-7,15-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
isopimara-7,15-dienol + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
isopimara-7,15-dienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
isopimara-7,15-dienol + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
isopimara-7,15-dienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
levopimaradienol + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
levopimaradienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
levopimaradienol + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
levopimaradienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
additional information
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
676795
Pinus taeda
?
-
-
-
-
additional information
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
676795
Picea sitchensis
?
-
-
-
-
additional information
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense, the enzyme catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine DRA biosynthesis
676795
Pinus taeda
?
-
-
-
-
additional information
the enzyme CYP720B1 is a multifunctional, multisubstrate cytochrome P450 monooxygenase
676795
Pinus taeda
?
-
-
-
-
additional information
the recombinant enzyme catalyzed the oxidation of multiple diterpene alcohol and aldehydes. It is not able to oxidize abietadiene. No activity with neoabietadienol or neoabietadienal
676795
Pinus taeda
?
-
-
-
-
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
assay at; assay at
Pinus taeda
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.5
7.6
-
Pinus taeda
7.6
-
assay at
Pinus taeda
pH Range
pH Minimum
pH Maximum
Commentary
Organism
7
8
about 80% of maximal activity at pH 7.0 and 8.0
Pinus taeda
Cofactor
Cofactor
Commentary
Organism
Structure
cytochrome P450
-
Pinus taeda
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
additional information
the enzyme expression is induced upon simulated insect attack using methyl jasmonate treatment of loblolly pine
Pinus taeda
Cloned(Commentary) (protein specific)
Commentary
Organism
CYPA1, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis
Picea sitchensis
CYPA2, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis
Picea sitchensis
CYPA, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis
Pinus taeda
CYPB, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis
Pinus taeda
CYPC, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis
Pinus taeda
CYP720B1, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, DNA and amino acid sequence determination and analysis
Pinus taeda
CYP720B1, functional cDNA screening and expression as FLAG-tagged protein in Saccharomyces cerevisiae, de novo diterpenoid formation in metabolically engineered yeast, overview
Pinus taeda
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
cytochrome P450
-
Pinus taeda
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
Michaelis–Menten kinetics, recombinant enzyme
Pinus taeda
0.0005
-
abietadienal
pH 7.6, 30°C
Pinus taeda
0.0005
-
abietadienal
pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0006
-
dehydroabietadienal
pH 7.6, 30°C
Pinus taeda
0.0006
-
dehydroabietadienal
pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0006
-
isopimaradienal
pH 7.6, 30°C
Pinus taeda
0.0006
-
isopimaradienal
pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0008
-
abietadienol
pH 7.6, 30°C
Pinus taeda
0.0008
-
abietadienol
pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0015
-
isopimara-7,15-dienol
pH 7.6, 30°C
Pinus taeda
0.0015
-
isopimaradienol
pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0019
-
levopimaradienol
pH 7.6, 30°C
Pinus taeda
0.0019
-
levopimaradienol
pH 7.6, 30°C, recombinant enzyme
Pinus taeda
0.0053
-
dehydroabietadienol
pH 7.6, 30°C
Pinus taeda
0.0053
-
dehydroabietadienol
pH 7.6, 30°C, recombinant enzyme
Pinus taeda
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Picea sitchensis
-
-
microsome
-
Pinus taeda
-
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
abieta-7,13-dien-18-ol + 2 [reduced NADPH-hemoprotein reductase] + 2 O2
Pinus taeda
-
abieta-7,13-dien-18-oate + 2 [oxidized NADPH-hemoprotein reductase] + 3 H2O
-
-
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
Pinus taeda
PtAO catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine diterpene resin acid biosynthesis
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
additional information
Pinus taeda
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
?
-
-
-
additional information
Picea sitchensis
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
?
-
-
-
additional information
Pinus taeda
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense, the enzyme catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine DRA biosynthesis
?
-
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
additional information
CYP720B1 tissue profiling
Pinus taeda
-
stem
-
Pinus taeda
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
substrate specificity, overview
Pinus taeda
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(13S)-pimara-7,15-dien-18-al + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
(13S)-pimara-7,15-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
abieta-7,13-dien-18-al + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
abieta-7,13-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
abieta-7,13-dien-18-ol + 2 [reduced NADPH-hemoprotein reductase] + 2 O2
-
676795
Pinus taeda
abieta-7,13-dien-18-oate + 2 [oxidized NADPH-hemoprotein reductase] + 3 H2O
-
-
-
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
PtAO catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine diterpene resin acid biosynthesis
676795
Pinus taeda
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
abietadienal + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
abietadienoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
abietadienol + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
abietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
dehydroabietadienal + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
dehydroabietadienoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
dehydroabietadienal + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
dehydroabietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
dehydroabietadienol + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
dehydroabietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
dehydroabietadienol + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
dehydroabietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
isopimara-7,15-dienal + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
isopimara-7,15-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
isopimara-7,15-dienol + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
isopimara-7,15-dienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
isopimara-7,15-dienol + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
isopimara-7,15-dienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
levopimaradienol + [reduced NADPH-hemoprotein reductase] + O2
-
676795
Pinus taeda
levopimaradienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
levopimaradienol + [reduced NADPH-hemoprotein reductase] + O2
oxidation at C-18
676795
Pinus taeda
levopimaradienal + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
additional information
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
676795
Pinus taeda
?
-
-
-
-
additional information
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
676795
Picea sitchensis
?
-
-
-
-
additional information
the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense, the enzyme catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine DRA biosynthesis
676795
Pinus taeda
?
-
-
-
-
additional information
the enzyme CYP720B1 is a multifunctional, multisubstrate cytochrome P450 monooxygenase
676795
Pinus taeda
?
-
-
-
-
additional information
the recombinant enzyme catalyzed the oxidation of multiple diterpene alcohol and aldehydes. It is not able to oxidize abietadiene. No activity with neoabietadienol or neoabietadienal
676795
Pinus taeda
?
-
-
-
-
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
assay at
Pinus taeda
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.5
7.6
-
Pinus taeda
7.6
-
assay at
Pinus taeda
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
7
8
about 80% of maximal activity at pH 7.0 and 8.0
Pinus taeda
Other publictions for EC 1.14.14.145
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
666567
Ro
Diterpene resin acid biosynthe ...
Pinus taeda
Phytochemistry
67
1572-1578
2006
-
-
1
-
-
-
-
-
1
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
676795
Ro
Loblolly pine abietadienol/abi ...
Picea sitchensis, Pinus taeda
Proc. Natl. Acad. Sci. USA
102
8060-8065
2005
1
-
2
-
-
-
-
9
2
-
-
9
-
11
-
-
-
-
-
2
1
-
25
-
1
-
-
-
2
1
-
1
-
-
-
1
-
7
1
-
-
-
-
-
-
15
7
-
-
9
-
-
-
-
-
2
1
-
25
-
2
-
-
-
2
1
-
-
-
-
-
-
-
-
690605
Funk
Diterpenoid resin acid biosynt ...
Abies grandis, Pinus contorta
Arch. Biochem. Biophys.
308
258-266
1994
-
-
-
-
-
-
6
1
2
-
-
2
-
2
-
-
-
-
-
2
-
-
2
-
2
-
-
-
2
1
-
3
-
-
5
-
-
-
3
-
-
-
5
6
-
1
2
-
-
2
-
-
-
-
-
2
-
-
2
-
2
-
-
-
2
1
-
-
-
-
-
-
-
-
694704
Funk
Regulation of oleoresinosis in ...
Abies grandis
Plant Physiol.
106
999-1005
1994
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-