BRENDA - Enzyme Database show
show all sequences of 1.14.14.162

CYP93G2 is a flavanone 2-hydroxylase required for C-glycosylflavone biosynthesis in rice

Du, Y.; Chu, H.; Chu, I.K.; Lo, C.; Plant Physiol. 154, 324-333 (2010)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
transgenic Arabidopsis overexpressing CYP93G2 or coexpressing CYP93G2 and OsCGT accumulates 2-hydroxyflavanone derivatives
Oryza sativa
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
eriodictyol+ [reduced NADPH-hemoprotein reductase] + O2
Oryza sativa
-
2-hydroxyeriodictyol + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
naringenin + [reduced NADPH-hemoprotein reductase] + O2
Oryza sativa
-
2-hydroxynaringenin + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Oryza sativa
Q5VRI5
subsp. japonica
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
eriodictyol+ [reduced NADPH-hemoprotein reductase] + O2
-
748966
Oryza sativa
2-hydroxyeriodictyol + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
naringenin + [reduced NADPH-hemoprotein reductase] + O2
-
748966
Oryza sativa
2-hydroxynaringenin + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
Cofactor
Cofactor
Commentary
Organism
Structure
cytochrome P-450
a cytochrome P-450 (heme thiolate) enzyme
Oryza sativa
Cloned(Commentary) (protein specific)
Commentary
Organism
transgenic Arabidopsis overexpressing CYP93G2 or coexpressing CYP93G2 and OsCGT accumulates 2-hydroxyflavanone derivatives
Oryza sativa
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
cytochrome P-450
a cytochrome P-450 (heme thiolate) enzyme
Oryza sativa
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
eriodictyol+ [reduced NADPH-hemoprotein reductase] + O2
Oryza sativa
-
2-hydroxyeriodictyol + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
naringenin + [reduced NADPH-hemoprotein reductase] + O2
Oryza sativa
-
2-hydroxynaringenin + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
eriodictyol+ [reduced NADPH-hemoprotein reductase] + O2
-
748966
Oryza sativa
2-hydroxyeriodictyol + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
naringenin + [reduced NADPH-hemoprotein reductase] + O2
-
748966
Oryza sativa
2-hydroxynaringenin + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
General Information
General Information
Commentary
Organism
malfunction
knocking down Os06g01250 in rice (Oryza sativa subsp. japonica Zhonghua 11) preferentially depletes the accumulation of C-glycosylapigenin, C-glycosylluteolin, and C-glycosylchrysoeriol but does not affect the levels of tricin
Oryza sativa
metabolism
the enzyme channels flavanones to C-glycosylflavone biosynthesis in rice
Oryza sativa
General Information (protein specific)
General Information
Commentary
Organism
malfunction
knocking down Os06g01250 in rice (Oryza sativa subsp. japonica Zhonghua 11) preferentially depletes the accumulation of C-glycosylapigenin, C-glycosylluteolin, and C-glycosylchrysoeriol but does not affect the levels of tricin
Oryza sativa
metabolism
the enzyme channels flavanones to C-glycosylflavone biosynthesis in rice
Oryza sativa
Other publictions for EC 1.14.14.162
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
748594
Vanegas
Indirect and direct routes to ...
Oryza sativa Japonica Group
Microb. Cell Fact.
17
107
2018
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748966
Du
CYP93G2 is a flavanone 2-hydr ...
Oryza sativa
Plant Physiol.
154
324-333
2010
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1
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5
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2
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655536
Akashi
Identification of a cytochrome ...
Glycyrrhiza echinata
FEBS Lett.
431
287-290
1998
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1
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657025
Otani
Licodione synthase, a cytochro ...
Glycyrrhiza echinata
Plant Physiol.
105
1427-1432
1994
1
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3
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1
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1
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