Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-heptyl-4-hydroxyquinoline N-oxide | 0.1 mM, 236% stimulation | Candida albicans |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-hydroxymercuribenzoate | 1 mM, 35% inhibition | Candida albicans | |
antimycin A | 0.1 mM, 44% inhibition | Candida albicans | |
bovine serum albumin | - |
Candida albicans | |
chloromercuriphenylsulfonate | 1 mM, 35% inhibition | Candida albicans | |
Cu2+ | 5 mM, 99% inhibition | Candida albicans | |
deoxycholate | - |
Candida albicans | |
N-ethylmaleimide | 1 mM, 35% inhibition | Candida albicans | |
rotenone | 0.1 mM, 67% inhibition | Candida albicans | |
Triton X-100 | - |
Candida albicans |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.05 | - |
squalene | - |
Candida albicans |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Candida albicans | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
- |
- |
Storage Stability | Organism |
---|---|
-20°C, 5 d, 75% loss of activity | Candida albicans |
stable for several months in liquid nitrogen | Candida albicans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
squalene + NAD(P)H + O2 | - |
Candida albicans | (S)-squalene-2,3-epoxide + NADP+ + H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | required for activity | Candida albicans | |
additional information | FMN cannot replace FAD as cofactor | Candida albicans |