Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | heme oxygenase-1 is induced by tert-butylhydroquinone and by deltamethrin via activation of Nrf2, overview | Rattus norvegicus |
Cloned (Comment) | Organism |
---|---|
semiquantitative RT-PCR expression analysis of HO-1 | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
heme + AH2 + O2 | Rattus norvegicus | the gene encoding HO-1 is a Nrf2-regulated gene. NF-E2 related factor 2 activation and heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin-mediated oxidative stress in PC12 cells, e.g. by H2O2 and 6-hydroxydopamine | biliverdin + Fe2+ + CO + A + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P06762 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
PC-12 cell | a adrenal pheochromocytoma cell line | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
heme + AH2 + O2 | - |
Rattus norvegicus | biliverdin + Fe2+ + CO + A + H2O | - |
? | |
heme + AH2 + O2 | the gene encoding HO-1 is a Nrf2-regulated gene. NF-E2 related factor 2 activation and heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin-mediated oxidative stress in PC12 cells, e.g. by H2O2 and 6-hydroxydopamine | Rattus norvegicus | biliverdin + Fe2+ + CO + A + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
heme oxygenase-1 | - |
Rattus norvegicus |
HO-1 | - |
Rattus norvegicus |