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Literature summary for 1.14.14.18 extracted from

  • Lee, G.H.; Kim, H.K.; Chae, S.W.; Kim, D.S.; Ha, K.C.; Cuddy, M.; Kress, C.; Reed, J.C.; Kim, H.R.; Chae, H.J.
    Bax inhibitor-1 regulates endoplasmic reticulum stress-associated reactive oxygen species and heme oxygenase-1 expression (2007), J. Biol. Chem., 282, 21618-21628.
    View publication on PubMed
Search for more literature for 1.14.14.18

Protein Variants

Protein Variants Comment Organism
additional information HO-1 expression is enhanced in BI-1 transfected cells compared to untransfected cells, phenotype, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-
microsome
-
 Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens HO-1 is involved in the function of bax inhibitor-1, BI-1, an anti-apoptotic protein that is located in endoplasmic reticulum membranes and protects cells from endoplasmic reticulum stress-induced apoptosis. For BI-1 associated function, HO-1 expression is induced by nuclear factor erythroid 2-related factor 2, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P09601
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-
HT-1080 cell a fibrosarcoma cell line Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information HO-1 is involved in the function of bax inhibitor-1, BI-1, an anti-apoptotic protein that is located in endoplasmic reticulum membranes and protects cells from endoplasmic reticulum stress-induced apoptosis. For BI-1 associated function, HO-1 expression is induced by nuclear factor erythroid 2-related factor 2, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
heme oxygenase-1
-
 Homo sapiens
HO-1
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Homo sapiens