Literature summary for 1.14.14.18 extracted from

Lin, H.H.; Lai, S.C.; Chau, L.Y.
Heme oxygenase-1/carbon monoxide induces vascular endothelial growth factor expression via p38 kinase-dependent activation of Sp1 (2011), J. Biol. Chem., 286, 3829-3838.

Search for more literature for 1.14.14.18

Cloned(Commentary)

Cloned (Comment)	Organism
adenovirus-mediated HO-1 transfection of Rattus norvegicus primary cardiomyocytes and H9C2 myocytes	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	adenovirus-mediated HO-1 transduction of Rattus norvegicus primary cardiomyocytes and H9C2 myocytes results in significant induction of VEGF expression, overview	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
heme oxygenase-1	-	Homo sapiens
HO-1	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	heme oxygenase-1/CO induces vascular endothelial growth factor expression via p38 kinase-dependent activation of Sp1. CO-induced VEGF promoter activation requires the binding of the Sp1 transcriptional factor to a cis-regulatory sequence located at the VEGF promoter. HO-1/CO induced p38-dependent phosphorylation of Sp1 at Thr453 and Thr739 both in vitro and in vivo	Homo sapiens

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Release 2023.1 (January 2023)