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Literature summary for 1.14.14.25 extracted from

  • Lund, E.G.; Guileyardo, J.M.; Russell, D.W.
    cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain (1999), Proc. Natl. Acad. Sci. USA, 96, 7238-7243.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.14.25

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-
endoplasmic reticulum
-
 Mus musculus 5783
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is a mediator of cholesterol homeostasis in the brain ?
-
 ?
additional information Mus musculus the enzyme is a mediator of cholesterol homeostasis in the brain ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9Y6A2
-
-
Mus musculus Q9WVK8
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain predominantly expressed in Mus musculus
-
brain predominantly expressed in. The 24-hydroxylase protein is first detected in the brain of mice at birth and continues to accumulate with age Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is a mediator of cholesterol homeostasis in the brain Homo sapiens ?
-
 ?
additional information the enzyme is a mediator of cholesterol homeostasis in the brain Mus musculus ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
cytochrome P-450
-
 Homo sapiens
cytochrome P-450
-
 Mus musculus