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Literature summary for 1.14.14.32 extracted from
- Chimerogenesis in estimation of specificity and pathway directions for cytochrome P45017alpha catalyzed reactions (2004), Biochemistry (Moscow), 69, 364-375.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | chimeric constructions of enzyme from Bos taurus and from Cavia porcellus, structural element responsible for switching activity between DELTA4- or DELTA5-pathway is located in the region of polypeptide chain coded by exons II-V of CYP17 gene | Cavia porcellus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cavia porcellus | Q64410 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 17alpha-hydroxyprogesterone + ? | - |
Cavia porcellus | androstenedione + ? | - |
? |  |
| additional information | enzyme catalyzes both 17alpha-hydroxylation of steroids, EC 1.14.99.9, and 17,20-lyase reaction, lyase activity is realized only with 17alpha-hydroxyprogesterone | Cavia porcellus | ? | - |
? | |
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Release 2023.1 (January 2023)
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