Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3beta-hydroxy-17-(50-[30-methyl]-10,20,40-oxadiazolyl)androst-5,16-diene | compound displays in vitro cytotoxic activity against HeLa cells, MCF-7 cells, A-2780 cells and A-431 cells which are higher than or comparable to that of the reference cisplatin | Homo sapiens | |
3beta-hydroxy-17-(50-[30-methyl]-10,20,40-oxadiazolyl)androst-5,16-diene | - |
Rattus norvegicus | |
abiraterone | - |
Rattus norvegicus | |
ketoconazole | - |
Rattus norvegicus | |
O-3beta-acetoxyandrost-5,16-diene-17-acyl-p-methoxybenzamidoxime | compound displays in vitro cytotoxic activity against HeLa cells, MCF-7 cells, A-2780 cells and A-431 cells which are higher than or comparable to that of the reference cisplatin | Homo sapiens | |
O-3beta-acetoxyandrost-5,16-diene-17-acylacetamidoxime | compound displays in vitro cytotoxic activity against HeLa cells, MCF-7 cells, A-2780 cells and A-431 cells which are higher than or comparable to that of the reference cisplatin | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Rattus norvegicus | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000012 | - |
pH 7.3, 37°C | Rattus norvegicus | abiraterone | |
0.000032 | - |
pH 7.3, 37°C | Rattus norvegicus | ketoconazole | |
0.00006 | - |
pH 7.3, 37°C | Rattus norvegicus | 3beta-hydroxy-17-(50-[30-methyl]-10,20,40-oxadiazolyl)androst-5,16-diene |