BRENDA - Enzyme Database show
show all sequences of 1.14.14.79

CYP4F3B expression is associated with differentiation of HepaRG human hepatocytes and unaffected by fatty acid overload

Madec, S.; Cerec, V.; Plee-Gautier, E.; Antoun, J.; Glaise, D.; Salaun, J.P.; Guguen-Guillouzo, C.; Corlu, A.; Drug Metab. Dispos. 39, 1987-1996 (2011)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
Q08477
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
Hepa-RG cell
-
Homo sapiens
-
hepatocyte
-
Homo sapiens
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
9(10)-epoxystearic acid + [reduced NADPH-hemoprotein reductase] + O2
-
729628
Homo sapiens
18-hydroxy-9(10)-epoxystearic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
Hepa-RG cell
-
Homo sapiens
-
hepatocyte
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
9(10)-epoxystearic acid + [reduced NADPH-hemoprotein reductase] + O2
-
729628
Homo sapiens
18-hydroxy-9(10)-epoxystearic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
Expression
Organism
Commentary
Expression
Homo sapiens
expression is associated with differentiation of HepaRG cels and unaffected by fatty acid overload
additional information
Expression (protein specific)
Organism
Commentary
Expression
Homo sapiens
expression is associated with differentiation of HepaRG cels and unaffected by fatty acid overload
additional information
Other publictions for EC 1.14.14.79
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
728344
Nakano
CYP4V2 in Bietti’s crystalli ...
Homo sapiens
Mol. Pharmacol.
82
679-686
2012
-
-
1
-
1
-
-
-
2
-
2
1
-
2
-
-
1
-
-
15
-
-
3
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
1
-
-
-
-
-
2
-
2
1
-
-
-
1
-
15
-
-
3
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
729628
Madec
CYP4F3B expression is associat ...
Homo sapiens
Drug Metab. Dispos.
39
1987-1996
2011
-
-
-
-
-
-
-
-
-
-
-
-
-
1
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2
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1
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2
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
704996
Fer
Cytochromes P450 from family 4 ...
Homo sapiens
J. Lipid Res.
49
2379-2389
2008
-
-
-
-
-
-
3
-
-
-
-
-
-
1
-
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3
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3
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3
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-
-
-
-
730854
Harmon
Oxygenation of omega-3 fatty a ...
Homo sapiens
Prostaglandins Leukot. Essent. Fatty Acids
75
169-177
2006
-
-
-
-
-
-
3
-
-
-
-
-
-
1
-
-
-
-
-
-
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3
-
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3
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3
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