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Literature summary for 1.14.14.80 extracted from

  • Kawashima, H.; Kusunose, E.; Kikuta, Y.; Kinoshita, H.; Tanaka, S.; Yamamoto, S.; Kishimoto, T.; Kusunose, M.
    Purification and cDNA cloning of human liver CYP4A fatty acid omega-hydroxylase (1994), J. Biochem., 116, 74-80.
    View publication on PubMed
Search for more literature for 1.14.14.80

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
 x * 52000, SDS-PAGE, x * 59347, calculated Homo sapiens
59347
-
 x * 52000, SDS-PAGE, x * 59347, calculated Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q02928
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-
liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.7
-
 substrate undecanoic acid, omega-1-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C Homo sapiens
1
-
 substrate lauric acid, omega-1-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C Homo sapiens
3
-
 substrate tridecanoic acid, omega-1-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C Homo sapiens
8.5
-
 substrate tridecanoic acid, omega-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C Homo sapiens
12
-
 substrate undecanoic acid, omega-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C Homo sapiens
13.9
-
 substrate isomyristic acid, omega-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C Homo sapiens
14.8
-
 substrate lauric acid, omega-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C Homo sapiens
24.5
-
 substrate isolauric acid, omega-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isolauric acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens 11-hydroxyisolauric acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
isomyristic acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens 13-hydroxyisomyristic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
lauric acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens 12-hydroxylauric acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
additional information isoform CYP4A11 catalyzes the omega- and omega-1-hydroxylation of various fatty acids Homo sapiens ?
-
 ?
tridecanoic acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens 13-hydroxytridecanoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
undecanoic acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens 11-hydroxyundecanoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Subunits

Subunits Comment Organism
? x * 52000, SDS-PAGE, x * 59347, calculated Homo sapiens

Synonyms

Synonyms Comment Organism
cytochrome P450 4A11
-
 Homo sapiens