BRENDA - Enzyme Database show
show all sequences of 1.14.14.80

Differential expression and evolution of the Arabidopsis CYP86A subfamily

Duan, H.; Schuler, M.A.; Plant Physiol. 137, 1067-1081 (2005)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Arabidopsis thaliana
O23066
isoform CYP86A2
-
Arabidopsis thaliana
O80823
isoform CYP86A8
-
Arabidopsis thaliana
P48422
isoform CYP86A1
-
Arabidopsis thaliana
Q9CAD6
isoform CYP86A7
-
Arabidopsis thaliana
Q9LMM1
isoform CYP86A4
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
flower
; CYP86A2 transcripts are 2- to 10fold less abundant in seedling roots, mature roots, and flower; CYP86A8 transcripts are 2fold more abundant in flowers than in seedling shoots; highest expression
Arabidopsis thaliana
-
additional information
CYP86A2 transcripts are similarly abundant in most tissues analyzed, and 2- to 10fold less abundant in seedling roots, mature roots, and flower
Arabidopsis thaliana
-
root
CYP86A2 transcripts are 2- to 10fold less abundant in seedling roots, mature roots, and flower; isoform CYP86A1 transcripts are 20fold more abundant in mature roots than in seedling roots
Arabidopsis thaliana
-
rosette
older rosettes, low expression
Arabidopsis thaliana
-
seedling
abundant expression in seedling shoots; isoform CYP86A1, transcripts are 17fold more abundant in seedling roots than in seedling shoots; shoot and root, low expression
Arabidopsis thaliana
-
silique
;
Arabidopsis thaliana
-
stem
;
Arabidopsis thaliana
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
lauric acid + [reduced NADPH-hemoprotein reductase] + O2
-
734950
Arabidopsis thaliana
12-hydroxylauric acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
lauric acid + [reduced NADPH-hemoprotein reductase] + O2
substrate for isoforms CYP86A1, CYP86A2, CYP86A4, CYP86A7, CYP86A8
734950
Arabidopsis thaliana
12-hydroxylauric acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
flower
CYP86A2 transcripts are 2- to 10fold less abundant in seedling roots, mature roots, and flower
Arabidopsis thaliana
-
flower
highest expression
Arabidopsis thaliana
-
flower
-
Arabidopsis thaliana
-
flower
CYP86A8 transcripts are 2fold more abundant in flowers than in seedling shoots
Arabidopsis thaliana
-
additional information
CYP86A2 transcripts are similarly abundant in most tissues analyzed, and 2- to 10fold less abundant in seedling roots, mature roots, and flower
Arabidopsis thaliana
-
root
isoform CYP86A1 transcripts are 20fold more abundant in mature roots than in seedling roots
Arabidopsis thaliana
-
root
CYP86A2 transcripts are 2- to 10fold less abundant in seedling roots, mature roots, and flower
Arabidopsis thaliana
-
rosette
older rosettes, low expression
Arabidopsis thaliana
-
seedling
isoform CYP86A1, transcripts are 17fold more abundant in seedling roots than in seedling shoots
Arabidopsis thaliana
-
seedling
shoot and root, low expression
Arabidopsis thaliana
-
seedling
abundant expression in seedling shoots
Arabidopsis thaliana
-
silique
-
Arabidopsis thaliana
-
stem
-
Arabidopsis thaliana
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
lauric acid + [reduced NADPH-hemoprotein reductase] + O2
-
734950
Arabidopsis thaliana
12-hydroxylauric acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
lauric acid + [reduced NADPH-hemoprotein reductase] + O2
substrate for isoforms CYP86A1, CYP86A2, CYP86A4, CYP86A7, CYP86A8
734950
Arabidopsis thaliana
12-hydroxylauric acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
Expression
Organism
Commentary
Expression
Arabidopsis thaliana
CYP86A1 transcripts are repressed 2.4fold by 27h of iodoacetc acid treatment and5.9fold by 27 h of salicylic acid treatment; CYP86A4 transcripts are repressed 9.0fold by short-term treatment with 1-aminocyclopropane-1-carboxylic acid and induced 1.9fold by long-term treatment with 1-aminocyclopropane-1-carboxylic acid. CYP86A4 transcripts are repressed 3.6fold by 3 h of wounding and 2.4fold in etiolated seedlings; CYP86A7 transcripts are significantly repressed by 2 h of drought treatment, 3 h of salicylic acid and wounding treatments, 3 and 27 h of 1-aminocyclopropane-1-carboxylic acid and mannitol treatments, and in both etiolated and dark-adapted seedlings; CYP86A8 transcripts are repressed by 30 min of wounding
down
Arabidopsis thaliana
CYP86A2 transcripts are transiently induced 2.5fold by 3 h of wounding and abscisic acid treatment, 2.3fold by 3 h of mannitol treatment, 1.7fold by 3 h of iodoacetic acid treatment, 1.6fold by 3 h of clofibrate treatment, more continuously induced 2.0- and 1.9fold by 30 and 120 min of drought treatment, and induced 1.9- to 2.3fold in etiolated and dark-adapted seedlings; CYP86A4 transcripts are induced 1.9fold by long-term treatment with 1-aminocyclopropane-1-carboxylic acid and repressed 9.0fold by short-term treatment with 1-aminocyclopropane-1-carboxylic acid; CYP86A7 transcripts are transiently induced 1.9fold by 3 h of clofibrate treatment, more continuously induced 1.6 and 1.5fold by 3 and 27 h of methyl jasmonate treatment, and slowly induced 1.7fold by 27 h abscisic acid treatment; CYP86A8 transcripts are induced by 3-h iodoacetic acid and abscisic acid treatments
up
Expression (protein specific)
Organism
Commentary
Expression
Arabidopsis thaliana
CYP86A1 transcripts are repressed 2.4fold by 27h of iodoacetc acid treatment and5.9fold by 27 h of salicylic acid treatment
down
Arabidopsis thaliana
CYP86A4 transcripts are repressed 9.0fold by short-term treatment with 1-aminocyclopropane-1-carboxylic acid and induced 1.9fold by long-term treatment with 1-aminocyclopropane-1-carboxylic acid. CYP86A4 transcripts are repressed 3.6fold by 3 h of wounding and 2.4fold in etiolated seedlings
down
Arabidopsis thaliana
CYP86A7 transcripts are significantly repressed by 2 h of drought treatment, 3 h of salicylic acid and wounding treatments, 3 and 27 h of 1-aminocyclopropane-1-carboxylic acid and mannitol treatments, and in both etiolated and dark-adapted seedlings
down
Arabidopsis thaliana
CYP86A8 transcripts are repressed by 30 min of wounding
down
Arabidopsis thaliana
CYP86A2 transcripts are transiently induced 2.5fold by 3 h of wounding and abscisic acid treatment, 2.3fold by 3 h of mannitol treatment, 1.7fold by 3 h of iodoacetic acid treatment, 1.6fold by 3 h of clofibrate treatment, more continuously induced 2.0- and 1.9fold by 30 and 120 min of drought treatment, and induced 1.9- to 2.3fold in etiolated and dark-adapted seedlings
up
Arabidopsis thaliana
CYP86A4 transcripts are induced 1.9fold by long-term treatment with 1-aminocyclopropane-1-carboxylic acid and repressed 9.0fold by short-term treatment with 1-aminocyclopropane-1-carboxylic acid
up
Arabidopsis thaliana
CYP86A7 transcripts are transiently induced 1.9fold by 3 h of clofibrate treatment, more continuously induced 1.6 and 1.5fold by 3 and 27 h of methyl jasmonate treatment, and slowly induced 1.7fold by 27 h abscisic acid treatment
up
Arabidopsis thaliana
CYP86A8 transcripts are induced by 3-h iodoacetic acid and abscisic acid treatments
up
Other publictions for EC 1.14.14.80
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
746320
Zhang
Ablation of cytochrome P450 o ...
Mus musculus
Proc. Natl. Acad. Sci. USA
114
3181-3185
2017
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746560
Uehara
Marmoset cytochrome P450 4A11 ...
Callithrix jacchus
Xenobiotica
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553-561
2017
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744773
Han
Biochemical analysis of recom ...
Homo sapiens
Drug Metab. Pharmacokinet.
31
445-450
2016
1
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3
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17
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1
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3
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18
746057
Bjelica
Fatty acid omega-hydroxylases ...
Solanum tuberosum
Plant Cell Rep.
35
2435-2448
2016
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1
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744772
Saito
Functional characterization o ...
Homo sapiens
Drug Metab. Pharmacokinet.
30
119-122
2015
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1
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9
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7
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733174
Huang
Expression and characterizatio ...
Starmerella bombicola
Appl. Environ. Microbiol.
80
766-776
2014
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3
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744097
Huang
Expression and characterizati ...
Starmerella bombicola, Starmerella bombicola ATCC 22214
Appl. Environ. Microbiol.
80
766-776
2014
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1
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3
1
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28
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9
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36
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2
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6
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28
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36
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3
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3
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2
6
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744323
Kim
Kinetic analysis of lauric ac ...
Homo sapiens
Biochemistry
53
6161-6172
2014
1
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703412
Nakano
Expression and characterizatio ...
Homo sapiens
Drug Metab. Dispos.
37
2119-2122
2009
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1
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1
3
1
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1
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706321
Dobritsa
CYP704B1 is a long-chain fatty ...
Arabidopsis thaliana
Plant Physiol.
151
574-589
2009
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7
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733891
Van Bogaert
Importance of the cytochrome P ...
Starmerella bombicola
FEMS Yeast Res.
9
87-94
2009
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734431
Gatica
P450 CYP2C epoxygenase and CYP ...
Rattus norvegicus
J. Lipid Res.
48
924-934
2007
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676666
Benveniste
Evolutionary relationship and ...
Arabidopsis thaliana
Plant Sci.
170
326-338
2006
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734950
Duan
Differential expression and ev ...
Arabidopsis thaliana
Plant Physiol.
137
1067-1081
2005
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285382
Hoch
Structural determination of th ...
Homo sapiens, Rattus norvegicus
Arch. Biochem. Biophys.
373
63-71
2000
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25
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733243
Benveniste
CYP86A1 from Arabidopsis thali ...
Arabidopsis thaliana
Biochem. Biophys. Res. Commun.
243
688-693
1998
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734106
Hiratsuka
Sex and strain differences in ...
Mus musculus
J. Biochem.
119
340-345
1996
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734105
Kawashima
Purification and cDNA cloning ...
Homo sapiens
J. Biochem.
116
74-80
1994
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