Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Catharanthus roseus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
geraniol + [reduced NADPH-hemoprotein reductase] + O2 | Catharanthus roseus | - |
(6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Catharanthus roseus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
58CrPM cell | - |
Catharanthus roseus | - |
cell culture | G10H activity is correlated to the ability of the cells to accumulate terpenoid indole alkaloids. Alkaloid induction medium induces the enzyme, overview | Catharanthus roseus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
geraniol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Catharanthus roseus | (6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
G10H | - |
Catharanthus roseus |
geraniol 10-hydroxylase | - |
Catharanthus roseus |
Organism | Comment | Expression |
---|---|---|
Catharanthus roseus | alkaloid induction medium induces the enzyme, overview | up |
General Information | Comment | Organism |
---|---|---|
evolution | the enzyme belongs to the cytochrome-P450 monooxygenase family | Catharanthus roseus |
metabolism | the enzyme is involved in the 2-C-methyl-D-erythritol-4-phosphate/terpenoid metabolic pathway part of the iridoid pathway, overview. Induction of G10H is a requirement, but not the only, necessary to produce other terpenoid indole alkaloids than strictosidine | Catharanthus roseus |