Cloned (Comment) | Organism |
---|---|
overexpression in Escherichia coli | Lycoris radiata |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Lycoris radiata |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
trans-cinnamate + [reduced NADPH-hemoprotein reductase] + O2 | Lycoris radiata | the enzyme is involved in the biosynthesis of galanthamine | 4-hydroxycinnamate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lycoris radiata | A0A2Z4I2V7 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Lycoris radiata |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bulb | intermediate transcript level | Lycoris radiata | - |
flower | high transcript level, the transcriptional levels of LrPAL3 is positively associated with the galanthamine contents within the leaves and flowers, which suggested that the expression and function is coregulated and involved in the biosynthesis of galanthamine | Lycoris radiata | - |
leaf | intermediate transcript level. The transcriptional levels of LrPAL3 is positively associated with the galanthamine contents within the leaves and flowers, which suggested that the expression and function is coregulated and involved in the biosynthesis of galanthamine | Lycoris radiata | - |
root | low transcript level | Lycoris radiata | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
trans-cinnamate + [reduced NADPH-hemoprotein reductase] + O2 | - |
Lycoris radiata | 4-hydroxycinnamate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
trans-cinnamate + [reduced NADPH-hemoprotein reductase] + O2 | the enzyme is involved in the biosynthesis of galanthamine | Lycoris radiata | 4-hydroxycinnamate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
C4H | - |
Lycoris radiata |
cinnamic acid 4-hydroxylase | - |
Lycoris radiata |
LrC4H | - |
Lycoris radiata |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the biosynthesis of galanthamine, a Amaryllidaceae alkaloid, that is a clinically used drug for the treatment of Alzheimer's disease | Lycoris radiata |