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Literature summary for 1.14.15.24 extracted from
- Carotenoid hydroxylation - P450 finally! (2004), Trends Plant Sci., 9, 515-517.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | required for activity, the beta-hydroxlyase is a non-heme diiron enzyme | Arabidopsis thaliana |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alpha-carotene + reduced acceptor + H+ + O2 | - |
Arabidopsis thaliana | zeinoxanthin + acceptor + H2O | - |
? | |
| beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 | - |
Arabidopsis thaliana | cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? | |
| beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 | - |
Arabidopsis thaliana | zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O | - |
? | |
| cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 | - |
Arabidopsis thaliana | zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| carotenoid beta-ring hydroxylase | - |
Arabidopsis thaliana |
| CYP97a3 | - |
Arabidopsis thaliana |
| CYP97C1 | - |
Arabidopsis thaliana |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| Ferredoxin | reduced ferredoxin is required for activity | Arabidopsis thaliana | |
| additional information | NADPH is not required for activity | Arabidopsis thaliana |
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