Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P05108 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(20R,22R)-20,22-dihydroxy-cholesterol + 2 reduced adrenodoxin + O2 | - |
Homo sapiens | pregnenolone + 4-methylpentanal + 2 oxidized adrenodoxin + 2 H2O | - |
? | |
(22R)-22-hydroxycholesterol + 2 reduced adrenodoxin + O2 | - |
Homo sapiens | (20R,22R)-20,22-dihydroxycholesterol + 2 oxidized adrenodoxin + H2O | - |
? | |
additional information | compound I, i.e. ferryl porphyrin pi-cation radical, is the active species in each of the three sequential monooxygenation reactions by which P450scc catalytically converts Ch to pregnenolone | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP 11A1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | compound I, i.e. ferryl porphyrin pi-cation radical, is the active species in each of the three sequential monooxygenation reactions by which P450scc catalytically converts Ch to pregnenolone | Homo sapiens |