Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Bathocuproine sulfonate | slight activation | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Bos taurus | |
Ba2+ | weak inhibition | Bos taurus | |
bathophenanthroline sulfonate | - |
Bos taurus | |
Co2+ | - |
Bos taurus | |
Fe3+ | - |
Bos taurus | |
Ni2+ | - |
Bos taurus | |
Zn2+ | - |
Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Bos taurus | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | high spin Fe(III) in an environment of nearly axial symmetry | Bos taurus | |
Iron | 0.66 mol per mol of subunit | Bos taurus | |
phosphate | 0.62 mol per mol of subunit | Bos taurus | |
Zn2+ | 0.13 mol per mol of subunit | Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
210000 | 211000 | adrenal, gel filtration | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
from adrenal medulla | Bos taurus |
large scale | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal medulla | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.425 | - |
purified enzyme | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tyrosine + tetrahydrobiopterin + O2 | - |
Bos taurus | 3,4-dihydroxy-L-phenylalanine + dihydrobiopterin + H2O | 3,4-dihydroxy-L-phenylalanine is identical with dopa | ? |