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Literature summary for 1.14.18.1 extracted from

  • Oozeki, H.; Tajima, R.; Nihei, K.I.
    Molecular design of potent tyrosinase inhibitors having the bibenzyl skeleton (2008), Bioorg. Med. Chem. Lett., 18, 5252-5254.
    View publication on PubMed
Search for more literature for 1.14.18.1

Inhibitors

Inhibitors Comment Organism Structure
2-[2-(2,4-dihydroxyphenyl)ethyl]-5-(D-xylopyranosyloxy)phenyl D-xylopyranoside isolated from Chlorophytum arundinaceum (liliaceae) Agaricus bisporus
2-[2-(2,4-dihydroxyphenyl)ethyl]-5-hydroxyphenyl D-xylopyranoside isolated from Chlorophytum arundinaceum (liliaceae) Agaricus bisporus
4,4'-ethane-1,2-diyldibenzene-1,3-diol
-
 Agaricus bisporus
4-[2-(2,4-dihydroxyphenyl)ethyl]-3-hydroxyphenyl D-xylopyranoside isolated from Chlorophytum arundinaceum (liliaceae) Agaricus bisporus
kojic acid
-
 Agaricus bisporus

Organism

Organism UniProt Comment Textmining
Agaricus bisporus
-
-
-

Synonyms

Synonyms Comment Organism
tyrosinase
-
 Agaricus bisporus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00037
-
-
 Agaricus bisporus 4,4'-ethane-1,2-diyldibenzene-1,3-diol
0.00043
-
-
 Agaricus bisporus 4-[2-(2,4-dihydroxyphenyl)ethyl]-3-hydroxyphenyl D-xylopyranoside
0.00073
-
-
 Agaricus bisporus 2-[2-(2,4-dihydroxyphenyl)ethyl]-5-(D-xylopyranosyloxy)phenyl D-xylopyranoside
0.0016
-
 5times more potent than that of kojic acid Agaricus bisporus 2-[2-(2,4-dihydroxyphenyl)ethyl]-5-hydroxyphenyl D-xylopyranoside
0.0074
-
-
 Agaricus bisporus kojic acid