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Literature summary for 1.14.18.1 extracted from

  • Yi, W.; Wu, X.; Cao, R.; Song, H.; Ma, L.
    Biological evaluations of novel vitamin C esters as mushroom tyrosinase inhibitors and antioxidants (2009), Food Chem., 117, 381-386.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2-(3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hydroxyethyl 3,4,5-trihydroxybenzoate mixed-type inhibitor Agaricus bisporus
D-ascorbic acid-6-p-hydroxybenzoic acid ester irreversible inhibitor Agaricus bisporus

Organism

Organism UniProt Comment Textmining
Agaricus bisporus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-DOPA + O2
-
Agaricus bisporus dopaquinone + H2O
-
?

Synonyms

Synonyms Comment Organism
polyphenol oxidase
-
Agaricus bisporus
PPO
-
Agaricus bisporus
tyrosinase
-
Agaricus bisporus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.16
-
in 50 mM phosphate buffer (pH 6.8) for 10 min at 25°C Agaricus bisporus 2-(3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hydroxyethyl 3,4,5-trihydroxybenzoate
0.58
-
in 50 mM phosphate buffer (pH 6.8) for 10 min at 25°C Agaricus bisporus D-ascorbic acid-6-p-hydroxybenzoic acid ester