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Literature summary for 1.14.18.1 extracted from

  • Wu, B.; Chen, J.; Qu, H.; Cheng, Y.
    Complex sesquiterpenoids with tyrosinase inhibitory activity from the leaves of Chloranthus tianmushanensis (2008), J. Nat. Prod., 71, 877-880.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
8-O-methyltianmushanol
-
 Agaricus bisporus
kojic acid
-
 Agaricus bisporus
additional information atractylenolide III, isofuranodiene, glechomanolide, and chloranthalactone A exhibit no inhibition against tyrosinase Agaricus bisporus
tianmushanol
-
 Agaricus bisporus

Organism

Organism UniProt Comment Textmining
Agaricus bisporus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-DOPA + O2
-
 Agaricus bisporus dopaquinone + H2O
-
 ?

Synonyms

Synonyms Comment Organism
tyrosinase
-
 Agaricus bisporus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.243
-
 in 50 mM Na-phosphate buffer (pH 6.8), at 37°C Agaricus bisporus kojic acid
0.312
-
 in 50 mM Na-phosphate buffer (pH 6.8), at 37°C Agaricus bisporus 8-O-methyltianmushanol
0.358
-
 in 50 mM Na-phosphate buffer (pH 6.8), at 37°C Agaricus bisporus tianmushanol