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Literature summary for 1.14.19.1 extracted from
- An isothermal induction of DELTA9-desaturase in cultured carp hepatocytes (1996), Biochim. Biophys. Acta, 1302, 207-216.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| calf serum | - |
Cyprinus carpio | |
| additional information | desaturase expression is sensitive to hormonal manipulation | Cyprinus carpio |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | of hepatocytes | Cyprinus carpio | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 33800 | - |
x * 33800 for cold treated carp, SDS-PAGE | Cyprinus carpio |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cyprinus carpio | - |
L. | - |
| Cyprinus carpio L. | - |
L. | - |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O | cold exposure leads to an induced activity, in vivo cooling causes an activity induction of up to 15 to 30fold. Increase of desaturase synthesis by means of activated gene transcription. Transfer of cells to 10°C causes a smaller increase in activity compared to cells maintained at 30°C | Cyprinus carpio |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Cyprinus carpio | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| stearate + AH2 + O2 | - |
Cyprinus carpio | oleate + A + 2 H2O | - |
? |  |
| stearate + AH2 + O2 | - |
Cyprinus carpio L. | oleate + A + 2 H2O | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 33800 for cold treated carp, SDS-PAGE | Cyprinus carpio |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Cyprinus carpio |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.6 | - |
assay at | Cyprinus carpio |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Cyprinus carpio | |
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