Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ | Homo sapiens | rate-limiting enzyme involved in the synthesis of monounsaturated fatty acids, hepatic SCD1 activity may regulate fat accumulation in the liver and possibly protects from insulin resistance in obesity, overview | oleoyl-CoA + ferricytochrome b5 + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | hepatic SCD1 activity index correlates negatively with liver fat and positively with insulin sensitivity, overview | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ | - |
Homo sapiens | oleoyl-CoA + ferricytochrome b5 + H2O | - |
? | |
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ | rate-limiting enzyme involved in the synthesis of monounsaturated fatty acids, hepatic SCD1 activity may regulate fat accumulation in the liver and possibly protects from insulin resistance in obesity, overview | Homo sapiens | oleoyl-CoA + ferricytochrome b5 + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SCD1 | - |
Homo sapiens |
stearoyl-CoA desaturase 1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ferrocytochrome b5 | - |
Homo sapiens |