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Literature summary for 1.14.19.1 extracted from

  • Melhus, H.; Riserus, U.; Warensjoe, E.; Wernroth, L.; Jensevik, K.; Berglund, L.; Vessby, B.; Michaelsson, K.
    A high activity index of stearoyl-CoA desaturase is associated with increased risk of fracture in men (2008), Osteoporos. Int., 19, 929-934.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.19.1

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens due to a population-based, longitudinal cohort study of men, the risk of fracture is highest among men with the highest levels of SCD activity index, overview ?
-
 ?
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ Homo sapiens stearoyl-CoA desaturase converts saturated to monounsaturated fatty acids and is a key enzyme in lipogenesis, elevated levels of endogenous lipogenesis increase the risk of fracture and suggest a role for saturated fat in the pathogenesis of osteoporosis oleoyl-CoA + ferricytochrome b5 + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information due to a population-based, longitudinal cohort study of men, the risk of fracture is highest among men with the highest levels of SCD activity index, overview Homo sapiens ?
-
 ?
stearoyl-CoA + ferrocytochrome b5 + O2 + H+
-
 Homo sapiens oleoyl-CoA + ferricytochrome b5 + H2O
-
 ?
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ stearoyl-CoA desaturase converts saturated to monounsaturated fatty acids and is a key enzyme in lipogenesis, elevated levels of endogenous lipogenesis increase the risk of fracture and suggest a role for saturated fat in the pathogenesis of osteoporosis Homo sapiens oleoyl-CoA + ferricytochrome b5 + H2O
-
 ?

Synonyms

Synonyms Comment Organism
SCD
-
 Homo sapiens
stearoyl-CoA desaturase
-
 Homo sapiens