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Literature summary for 1.14.19.18 extracted from

  • Tonon, T.; Sayanova, O.; Michaelson, L.V.; Qing, R.; Harvey, D.; Larson, T.R.; Li, Y.; Napier, J.A.; Graham, I.A.
    Fatty acid desaturases from the microalga Thalassiosira pseudonana (2005), FEBS J., 272, 3401-3412.
    View publication on PubMed
Search for more literature for 1.14.19.18

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae strain InvSc1 Thalassiosira pseudonana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+ Thalassiosira pseudonana
-
 (4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
-
 ?
sphinganine + ferrocytochrome b5 + O2 + H+ Thalassiosira pseudonana the enzyme shows strong preference for dihydroxylated substrates ?
-
 ?

Organism

Organism UniProt Comment Textmining
Thalassiosira pseudonana Q4G2T2
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+
-
 Thalassiosira pseudonana (4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
-
 ?
sphinganine + ferrocytochrome b5 + O2 + H+ the enzyme shows strong preference for dihydroxylated substrates Thalassiosira pseudonana ?
-
 ?

Synonyms

Synonyms Comment Organism
DELTA8-sphingolipid desaturase
-
 Thalassiosira pseudonana
DesB
-
 Thalassiosira pseudonana
sphinganine DELTA8-desaturase
-
 Thalassiosira pseudonana

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
 Thalassiosira pseudonana