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Literature summary for 1.14.19.5 extracted from
- Biosynthesis of 10,12-dienoic fatty acids by a bifunctional DELTA11 desaturase in Spodoptera littoralis (2006), Insect Biochem. Mol. Biol., 36, 634-641.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed as polyhistidine-tagged protein in elongase 1 and DELTA9 desaturase-deficient yeast cells | Spodoptera littoralis |
| expression in Saccharomyces cerevisiae DELTAelo1/DELTAole mutant strain, which is both elongase 1 and DELTA9 desaturase-deficient, using a Cu+2 inducible expression vector, the recombinant expression leads to producing large quantities of C11-monounsaturated fatty acids, mainly (Z)-11-hexadecenoic acid, (E,E)-10,12-tetradecadienoic acid, minor amounts of (E,Z)-10,12-hexadecadienoic acid, and very low amounts of (E,Z)-10,12-tetradecadienoic isomer | Spodoptera littoralis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Spodoptera littoralis | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| long-chain acyl-CoA + reduced acceptor + O2 = DELTA11-acyl-CoA + acceptor + 2 H2O | active site modeling | Spodoptera littoralis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (Z)-11-tetradecenoyl-CoA + reduced acceptor + O2 | (E,E)-10,12-tetradecadienoic acid is produced from (Z)-11-tetradecenoic acid by desaturation and concomitant migration of the precursor double bond | Spodoptera littoralis | (E,E)-10,12-tetradecadienoyl-CoA + acceptor + H2O | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| bifunctional DELTA11-desaturase | - |
Spodoptera littoralis |
| DELTA11 desaturase | - |
Spodoptera littoralis |
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