BRENDA - Enzyme Database show
show all sequences of 1.14.19.64

Molecular cloning and characterization of a cytochrome P450 in sanguinarine biosynthesis from Eschscholzia californica cells

Takemura, T.; Ikezawa, N.; Iwasa, K.; Sato, F.; Phytochemistry 91, 100-108 (2013)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2
Eschscholzia californica
-
(S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
(S)-tetrahydrocolumbamine + [reduced NADPH-hemoprotein reductase] + O2
Eschscholzia californica
-
(S)-tetrahydroberberine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Eschscholzia californica
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2
-
728446
Eschscholzia californica
(S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
(S)-tetrahydrocolumbamine + [reduced NADPH-hemoprotein reductase] + O2
-
728446
Eschscholzia californica
(S)-tetrahydroberberine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2
Eschscholzia californica
-
(S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
(S)-tetrahydrocolumbamine + [reduced NADPH-hemoprotein reductase] + O2
Eschscholzia californica
-
(S)-tetrahydroberberine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2
-
728446
Eschscholzia californica
(S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
(S)-tetrahydrocolumbamine + [reduced NADPH-hemoprotein reductase] + O2
-
728446
Eschscholzia californica
(S)-tetrahydroberberine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
Other publictions for EC 1.14.19.64
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
746047
Yahyazadeh
-
Cloning and characterization ...
Chelidonium majus
Plant Cell Physiol.
58
1421-1430
2017
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-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
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-
2
-
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3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
746447
Hori
Efficient microbial productio ...
Eschscholzia californica
Sci. Rep.
6
22201
2016
-
2
1
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
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-
-
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-
-
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-
-
-
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-
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2
1
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-
-
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-
-
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-
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-
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-
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-
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-
-
-
-
-
-
-
-
-
-
-
728446
Takemura
Molecular cloning and characte ...
Eschscholzia californica
Phytochemistry
91
100-108
2013
-
-
-
-
-
-
-
-
-
-
-
2
-
4
-
-
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2
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2
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2
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-
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-
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-
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-
711025
Diaz Chavez
Characterization of two methyl ...
Argemone mexicana
Arch. Biochem. Biophys.
507
186-193
2011
-
-
1
-
-
-
-
1
-
-
1
-
-
5
-
-
-
-
-
4
-
-
2
-
1
1
-
1
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
4
-
-
2
-
1
1
-
1
1
1
-
-
-
1
1
-
-
-
673579
Ikezawa
Molecular cloning and characte ...
Eschscholzia californica
FEBS J.
274
1019-1035
2007
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-
1
-
-
-
-
2
-
-
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3
-
7
-
-
-
-
-
3
2
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8
-
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-
-
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-
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1
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-
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2
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3
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3
2
-
8
-
-
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-
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-
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-
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-
395597
Bauer
-
Two methylenedioxy bridge form ...
Eschscholzia californica
Phytochemistry
30
2953-2961
1991
-
-
-
-
-
-
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1
1
-
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1
-
1
-
-
-
-
-
1
-
1
2
-
1
-
2
-
1
1
-
3
-
-
-
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-
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3
-
-
-
-
-
-
1
1
-
-
1
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-
-
-
-
1
-
1
2
-
1
-
2
-
1
1
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