KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.003 | - |
(R)-reticuline | - |
Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Sus scrofa | 5764 | - |
microsome | - |
Mus musculus | - |
- |
microsome | - |
Homo sapiens | - |
- |
microsome | - |
Rattus norvegicus | - |
- |
microsome | - |
Sus scrofa | - |
- |
microsome | - |
Bos taurus | - |
- |
microsome | - |
Ovis aries | - |
- |
mitochondrion | - |
Mus musculus | 5739 | - |
mitochondrion | light mitochondrial fraction | Sus scrofa | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
x * 50000, SDS-PAGE | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 | Sus scrofa | critical step in morphine biosynthesis | salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Homo sapiens | - |
very low activity | - |
Mus musculus | - |
- |
- |
Ovis aries | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 | highly regioselective and stereoselective enzyme | Sus scrofa | salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 | critical step in morphine biosynthesis | Sus scrofa | salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
(R/S)-orientaline + [reduced NADPH-hemoprotein reductase] + O2 | - |
Sus scrofa | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50000, SDS-PAGE | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | - |
Mus musculus | |
cytochrome P450 | - |
Homo sapiens | |
cytochrome P450 | - |
Rattus norvegicus | |
cytochrome P450 | - |
Bos taurus | |
cytochrome P450 | - |
Ovis aries | |
cytochrome P450 | enzyme contains cytochrome P450 | Sus scrofa | |
cytochrome P450 | 20 nmol cytochrome P450 per mg of enzyme | Sus scrofa | |
N5-Dinitrophenyl-D-ornithine methyl ester | - |
Bos taurus |